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Frequent Contributor
Posts: 104
Registered: ‎03-09-2010

OVM vs. Neuropeptide Facial Cream

This line is getting extremely confusing for me I am currently using Neuropeptide Facial Cream since 2009. OVM states 81% saw a reduction of fine lines and wrinkles NFC states 82% reported an improvement in fine lines and wrinkles.

OVM description states:

Why is it different: OVM is enhanced with eggshell membrane, vitamin A, and Dr. Perricone's unique carrier system to create a powerful bio-matrix technology. After 4 weeks of use in a consumer-use study of OVM, 81% of participants saw a reduction in the appearance of fine lines and wrinkles which gave their skin a younger appearance.

Neuropeptide Facial Cream description states:

Who is it for: All skin types. 82% of users reported an improvement in the appearance of fine lines and wrinkles, 70% reported their skin is firmer, and 85% reported their skin had a better glow.

I understand there are different ingredients in both, but, I wonder which one I should use for my fine lines and deep wrinkles?

Trusted Contributor
Posts: 1,328
Registered: ‎03-09-2010

Re: OVM vs. Neuropeptide Facial Cream

patf - I haven't watched the TSV presentation, but if QVC is placing the emphasis on "fine lines and wrinkles" with OVM, I'm a bit confused by that. If you surf over to perriconemd.com, you will see that the OVM video refers to improvements in "volume, cushion and firmness." There is no mention of wrinkles. There have been studies of hydrolyzed eggshell membrane. One article I read stated, Human skin has two types of collagen, one is type I collagen which forms heavy fibers to support tissue structure, the other is type III collagen which forms fine fibers to give tissue flexibility. Fetus and baby’s skin are rich of type III collagen, which however are decreasing as aging. The clinical study I read showed that the use of hydrolyzed eggshell membrane increased the production of type III collagen.
@(-_-)@ ~lyn~
Birman =^..^= Servant
Member since 04.2007

Trusted Contributor
Posts: 1,588
Registered: ‎03-18-2010

Re: OVM vs. Neuropeptide Facial Cream

If you want a critique of some of Perricone's products, go to the website Beautypedia.

Super Contributor
Posts: 1,456
Registered: ‎11-04-2013

Re: OVM vs. Neuropeptide Facial Cream

I have found his products overlap and it is confusing to say the least.

Frequent Contributor
Posts: 104
Registered: ‎03-09-2010

Re: OVM vs. Neuropeptide Facial Cream

On 1/11/2014 lyn in MI said: patf - I haven't watched the TSV presentation, but if QVC is placing the emphasis on "fine lines and wrinkles" with OVM, I'm a bit confused by that. If you surf over to perriconemd.com, you will see that the OVM video refers to improvements in "volume, cushion and firmness." There is no mention of wrinkles. There have been studies of hydrolyzed eggshell membrane. One article I read stated, Human skin has two types of collagen, one is type I collagen which forms heavy fibers to support tissue structure, the other is type III collagen which forms fine fibers to give tissue flexibility. Fetus and baby’s skin are rich of type III collagen, which however are decreasing as aging. The clinical study I read showed that the use of hydrolyzed eggshell membrane increased the production of type III collagen.

Thanks lyn I went over to the Perricone website and watched the video it surely does not mention anything about fine lines and wrinkles. I haven't watched a presentation of the TSV I only read the QVC description and it does mention it helps with fine lines and wrinkles.

I would have to assume that Perricone's website is the accurate description so I will pass on the OVM and continue with the NFC.


Super Contributor
Posts: 5,837
Registered: ‎03-01-2013

Re: OVM vs. Neuropeptide Facial Cream

If it is all THAT COMPLICATED... when it should not be... it should make you wonder shouldn't it??? $174.00 is a lot of money for three small products....!!! you would be better off putting that money down on some injections or botox.

Respected Contributor
Posts: 2,966
Registered: ‎05-30-2010

Re: OVM vs. Neuropeptide Facial Cream

Lyn, you have made me re-evaluate the OVM product. I have more of a problem with firmness than I do wrinkles. So when all the products say they are for wrinkles, I tend to pass. In your opinion, which current Perricone product (for firmness) would the OVM replace (or be used in combination with, perhaps)?

Frequent Contributor
Posts: 104
Registered: ‎03-09-2010

Re: OVM vs. Neuropeptide Facial Cream

On 1/11/2014 smokymtngal said:

Lyn, you have made me re-evaluate the OVM product. I have more of a problem with firmness than I do wrinkles. So when all the products say they are for wrinkles, I tend to pass. In your opinion, which current Perricone product (for firmness) would the OVM replace (or be used in combination with, perhaps)?


I'm not Lyn, but, I highly recommend the Neuropeptide Facial Cream for firmness. Since using this (2009) I can't pinch even a millimeter of the skin on my face. I make sure I bring it down below my jawline.

Respected Contributor
Posts: 2,966
Registered: ‎05-30-2010

Re: OVM vs. Neuropeptide Facial Cream

On 1/11/2014 patf said:
On 1/11/2014 smokymtngal said:

Lyn, you have made me re-evaluate the OVM product. I have more of a problem with firmness than I do wrinkles. So when all the products say they are for wrinkles, I tend to pass. In your opinion, which current Perricone product (for firmness) would the OVM replace (or be used in combination with, perhaps)?


I'm not Lyn, but, I highly recommend the Neuropeptide Facial Cream for firmness. Since using this (2009) I can't pinch even a millimeter of the skin on my face. I make sure I bring it down below my jawline.

patf, thank you for your response. I tried the neuropeptide facial cream years ago and don't remember liking it (maybe it was the smell, not sure). I do use and like the neuropeptide firming moisturizer but that's probably not as firming. I may have to give the NFC another try unless someone here can tell me if the OVM is just as good or better.

Occasional Contributor
Posts: 6
Registered: ‎04-06-2013

Re: OVM vs. Neuropeptide Facial Cream

Hi, Everyone

At the end of last night, I put the TSV on hold becuase I was also confused about the information I heard from Dana and information from the website. I hoped that by waiting I could stop at the NY store and get definitive information from their specialists and with their help might be able to figure this out. But that was just a wild dream, because when I called the store I was told that it was no longer open. (and there was no explanation as to why the NY location had closed).

So by phone, I gave the specialist a specific list of my biggest issues in descending order and as they pertained to the TSV -- beginning with a loss of firmness and my desire to restore the cushion, sagging of the jawline and a slight turkey neck, crepiness on the eyelids and crows feet around the eyes, fine lines, and general winter dryness. Her responses were rather startling.

Her recommended list totaled 8 items, and not one included Sub D, NP Facial Cream, OVM, the eye treatment, Photo Plasma, Cold Plasma or the NP Facial Cream. When questioned, she said that "individual products targeted to treat specific areas were much more successful." Not only is this is contrary to what's happenning throughout the entire skin care industry for more than a decade, the success of products that multi-task is evidenced by the sales of Cold Plasma, which the Perricone website still touts as their #1 best selling product of all time; and she said that Cold Plasma was a waste of time.

Now ladies, get ready for the next two: the specialist also said that Sub D was only for women with double chins, and didn't do anything to improve a sagging jawline or turkey neck, and that since I live in NYC that any SPF was unnecessary in winter and I wouldn't need it until April.

Later, in the day, in the middle of one of the TSV shows,Dana picked up a tube of the NPFC, and placed it very deliberately on tope of the OVM jar, saying, "I would never go a day without these two."

Shortly after that she talked about the instructions on the tube of the NP Facial Cream. They say that "Dr. Perricone recommends patting gently on targeted areas of the face…cheeks forehead and jawline. I've followed those instructions -- for years. But, today Dana said that the NPFC should be applied to the entire face and rubbed agressively into the skin, not patted. Referring to the tube, she said: "The instructions are wrong," and referring to the Perricone people, "I don't know why no one listens to me about this." Am I the only one who's patting targeted areas? If this is news to you too, begin applying to your entire face and as she said, massage it in.

So -- The website information is different than the host information and different than the specialist's informaton; and where is Dr. Perricone in all this? He's not a scientist, rarely appears on the show (unlike Peter Thomas Roth, Dr. Gross and Dr. Denese), and when he does, he barely speaks. It appears that the company is very disorganized and that there are communication as well as quality control issues.

As dreadful as it may sound, is it possible that the QVC selling technique (like many other manufacturers') is to deliberately, and always with equal intensity and fanfare, regularly present us with the newest, greatest and most important breakthrough of the day, and suggest that the product that was wonderful last month is now outdated and not good enough? Yes, of course, they would, and that's just fine -- as long as they're straightforward, consistent, and give us specific information so we can make educated choices. Are you listening Dr P? We shoudn't have to guess as much as we do with your products. The point should be to build a strong and loyal customer base.

But, there is no other skin care line on QVC, or in the retail market, that introduces so many new products in the same space of time; and that in and of itself is problematic unless there is a strong team in place. Having said all that….

This newest group is exciting, but I don't want to throw my money away as I did with NPFC. So, anyone with feedback or insight into this problem of inconsistent and overlapping iinformation, please come forward with your thoughts -- and if you know of a skin care line that will pick my neck and jawline off the floor, please share it with me. It's dropping as we speak!