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Super Contributor
Posts: 333
Registered: ‎03-22-2010

Re: Difference in Matrixyls???

Here is the item number to the Matrixyl 20% and Manuela explains it. Maybe you have watched it but for those who haven't for a while:

308-547. HTH.

Trusted Contributor
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Registered: ‎03-09-2010

Re: Difference in Matrixyls???

HappyDaze - the serum in the TTV is not Isomers Matrixyl™ 20%. It is Isomers Matrixyl™ Advanced Wrinkle Defense Serum.

They are two different products.
@(-_-)@ ~lyn~
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Re: Difference in Matrixyls???

On 10/24/2014 2cockers1cat said:
On 10/24/2014 HappyDaze said:
On 10/24/2014 lyn in MI said:
On 10/24/2014 HappyDaze said:
On 10/24/2014 hulagirl said:

I don't think any other product line uses as much Matrixyl in their products as Isomers....I've used it since she first offered it.

I believe isomers is 20% correct? I know NCN's is 25%.

I don't think Isomers has advised the total % of the 3 formulas of Matrixyl in the TTV Serum. We know that the % of Matrixyl included is 10%. We also know that Isomers states they always formulate with at least the minimum recommended use %. According to Sederma, the recommended use level of Matrixyl 3000 is 3% to 8% and the recommended use level of Mayrixyl Synthe 6 is 2%. Since the Adv. Serum contains 10% of Matrixyl, the total % of all three types should equal 15% to 20% or more.

so what is meant by the "20%" in the title of the product?

This is from Isomers description of 20% formulation:
Matrixyl 20% contains:

  • Matrixyl targets deep wrinkles & dermal matrix (plumps skin)
  • Matrixyl 3000 targets wrinkles and hydration (smooths surface)
  • 2 forms of the peptide in 300% above the clinical level
  • For all skin types. Ages 20+

Adding: For the first time Isomers has taken two key peptides of micro collagen (lab created collagen) and combined them in a synergistic blend of 10% each in our exclusive base.

Right, so there is 20% matrixyl in the formulation. That is all I was trying to clarify, as Lyn stated that Isomers doesn't state what % matrixyl is in the product.

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Re: Difference in Matrixyls???

On 10/24/2014 HappyDaze said:

Right, so there is 20% matrixyl in the formulation. That is all I was trying to clarify, as Lyn stated that Isomers doesn't state what % matrixyl is in the product.

HappyDaze - Isomers doesn't state the total % of the 3 Matrixyls in the TTV. The Matrixyl 20% is a different serum and it does not contain Matrixyl Synthe 6.
@(-_-)@ ~lyn~
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Re: Difference in Matrixyls???

Found some interesting info @ Sederma about the different types of Matrixyl...

Which one is better?
None! They are all different and perform different efficacy. For example, Sederma has recently demonstrated that Matrixyl® 3000 shows great results in repairing photo-aged skin and defragmented collagen network at the level of the dermis. The crow’s feet wrinkles decrease by 33% after applying a cream for two months. Matrixyl® synthe’6® stimulates the synthesis of collagen but also five other major constituents of the skin. The volume of the forehead wrinkles can decrease by 31% until a dramatic smoothing effect in just two months.

All those products underwent extensive research for efficacy and safety, and are patented. Matrixyl®, Matrixyl® synthe’6® and Matrixyl Inside® are trademarks of Sederma SAS. Discover the Matrixyl Inside® range here.
@(-_-)@ ~lyn~
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Re: Difference in Matrixyls???

She's on right now pitching the TSV with loads of details, too many in fact for me to keep up with. Some might say confusing, especially with such an extensive line. Says Isomers was in on the naming of Matrixyl 3000.

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Re: Difference in Matrixyls???

On 10/24/2014 hulagirl said:

I don't think any other product line uses as much Matrixyl in their products as Isomers....I've used it since she first offered it.

If there is no information as to the strength of this Matrixyl serum, then how would anyone know that it contains the highest percentage?

The only thing I found in its description is "8% Matrixyl concentrate in the formulation at its optimum tested level."

I don't know how that correlates to the fact that my NCN is labeled as being 25 percent.

ETA: I realized that you may be speaking more generally about her use of Matrixyl in a variety of her products. But still, I'm surprised that she hasn't included the percentage in this serum in the product description.


~Who in the world am I? Ah, that's the great puzzle~ Lewis Carroll, Alice in Wonderland
Trusted Contributor
Posts: 1,141
Registered: ‎03-27-2010

Re: Difference in Matrixyls???

I tried both of Isomer's matrixyls and didn't notice much from either. I'd suggest trying NCN's Multiactive Peptide Matrixyl serum 25% which has the following in it:

  1. Matrixyl
  2. Matrixyl 3000
  3. Matrixyl Synthe'6
  4. Acetyl Tetrapeptide-9
  5. Wild Mushroom Extract
  6. Soy Rice Peptides
  7. Pepha-tight

The sample size is 1oz and runs $45 and 2.5 oz is $85.

Edited to add: I agree with suzyQ3 - and she uses NCN's matrixyl serum too.

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Regular Contributor
Posts: 194
Registered: ‎03-09-2010

Re: Difference in Matrixyls???

Wow..lots of great info here. Thx everyone. I caved and got both the TTV and the dry skin kit with the rPur. I'm thinking of adding some more matrixyl defense into my one serum during the day. When I'm done I may try the NCN brand. But I'll have enuf stash for at least. 2 years! Lol
Respected Contributor
Posts: 3,791
Registered: ‎03-13-2010

Re: Difference in Matrixyls???

On 10/24/2014 beautybuster said: I love her and her products. I just want to simplify. I have so many brown bottles! Can't I just have one serum in am and one for the pm that has everything in it I need? Lol I don't think that's asking too much!

I agree that there are so many products and it can be confusing trying to figure out what to use. Although I think that's why she made the All in One series which does simplify. But that doesn't mean it has everything in it you need so you might want to add something else to cocktail with it, I suppose.

As to the Matrixyl, I've never used the "advanced" and didn't get the TTV, but I did use another one from Isomers (which came in a previous TTV with a tinted cream) and I saw no difference using that.