h@pitdakota wrote:
For the hydroxcholorquine situation, let the doctors do their jobs.
No one here knows specific information about the medication and unfortunately the issue has become political. It should not be. There are multiple reasons that some might not be placed on this medication. One is that there has in the past been a concern about its ability to interfere with the electrical cycle of the heart that conducts a normal heart beat in some individuals. That disturbance has been deadly for some in the past.
With all of the controlled trials that are going on now they will learn quite a bit more about this medication, which is a positive. Maybe the cardiac risk is not as great as they once thought? Maybe it is greater? Maybe it works for Covid-19 in controlled studies, maybe it doesn't. And maybe the controlled studies identify the medication is risky for those with some type of abnormal heart rhythm, but effective for others. The point is we don't know yet.
At any rate, lay people that don't understand the basics of pharmacokinetics or pharmacodynamics don't need to be touting what should or should not happen based on just something they hear.
I think there is concern by the medical community that some will try to obtain it through other measures not understanding the existing concerns and contraindications regarding the medication. In fact, I know a pharmacist that told about a request from someone he knew to just slip him about 15 tablets. There just had to be a way he could do it and write it off as an abnormality due to the high demand of the medication. Of course, he would never do that.....but it is kind of crazy what is going on out there with people that don't understand the importance of having your doctor work with you in making the decision.
Not to mention that there are beaucoup medications out there under clinical trial right now for treatment of covid-19 and multiple areas that are researching vaccines. There are also some that are very hopeful regarding a medication they tried with Ebola....remdesivir. One of the patients in Washington was placed on this and improved within 24 hours. Now, will that hold out in controlled studies? Who knows.
Fingers crossed that one of them offers some hope in treatment. But in the meantime, why not leave it to the ones that are conducting the clinical trials or the specific doctors using it without a clinical trial. Just because someone wants to play a doctor on TV, at home or on a discussion board, doesn't mean that is the best approach. We just need to let them do the studies and hope for the best.
And by the way, there is something known in research in which they abruptly stop a study. It doesn't happen often, but when the study group has such a better outcome than the control arm, or the arm receiving care according to current treatment they will stop the study. At that point it becomes unethical to withhold the experimental treatment from all people when that arm of the study is outperforming the other 2 arms in the study to a significant degree.
As I said, doesn't happen all that often, but when it does they will stop the study where they are & publish results quickly to re-establish new treament guidelines.
In the meantime, I think we just need to let them do the research and hope that something out there turns out beneficial in the treatment. Doesn't matter what it is....just something that is safe and effective.
@pitdakota
Wish everyone the best success with this drug. I took it for another reason, and had a bad reaction. If it works Great, but as you point out, it needs a good bit more research.
Thanks for the information.
"Animals are not my whole world, but they have made my world whole" ~ Roger Caras
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