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02-20-2026 01:33 PM
Companies now are making PDRN from green tea. Innisfree is also cruelty-free
02-20-2026 01:46 PM
PDRN molecules are much too large to penetrate the skin. Topicals containing it might help with hydration by maintaining hydration at the surface.
02-20-2026 02:18 PM
@SilleeMee wrote:PDRN molecules are much too large to penetrate the skin. Topicals containing it might help with hydration by maintaining hydration at the surface.
So I jumped on the bandwagon too soon? It wouldn't be the first time. 😆🤦♀️
02-20-2026 02:47 PM
Where PDRN is most beneficial is beneath the surface. It's available as an injectable at some medispas but it is not an FDA-approved product or procedure.
02-20-2026 04:29 PM
Medicube has one made from roses.
02-20-2026 04:30 PM - edited 02-20-2026 04:39 PM
HSN and Amz have the same one not made from salmon, made from green caviar aka sea grapes.
02-20-2026 04:41 PM
I see some brands on Amz that are called concentrates, you just add a drop or 2 to any other serum or cream, I think that could be more beneficial than using just the serum. PDRN seems to be the rage now in K Beauty
02-20-2026 05:27 PM
I know there is PDRN in one of Numbuzin essences but can't remember which one. I didn't buy it because that was in it though. So, what is PDRN?
02-20-2026 05:45 PM - edited 02-20-2026 05:47 PM
@JudyL it started out as fish sp3rm, That was a no go for many not wanting to put that on their face. It's been popular in Korean skincare.
PDRN = Polydeoxyribonucleotide, a DNA fragment extracted from salmon sp3rm (yes, really) that's used in medical treatments for skin regeneration and wound healing. It's been used in Korea for years in dermatology clinics as an injectable "skin booster," especially for aging or post-procedure skin.
02-20-2026 06:02 PM
I am having issues with one of my contact lenses today and my first reading of this headline was PORN NOT from fish.
Well, it got my attention anyway.
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