Mostly for me, no. I use O'Keefe's Working Hands nightly and have been adding Dr. Nassif's face serum as an occlusive on top until I run out of it. I can't use it on my face since it causes hard bumps. I do, however, have one finger that's a problem, and I'm always trying to find something to soften it. It tends to overgrow and I'm bad at picking at it. I used to get a lot of hangnails in that finernail and I would pull them out, but it got infected once. I've had trouble with it ever since. I always use any exfoliant I put on my face on it too, like the Dr. Nassif Peel Pads. I've also used a much higher % glycolic acid pad on it in the past.
BTW, I no longer pull out my hangnails, but clip them with the nail clippers as close as possible.