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01-15-2021 05:57 PM
@Lipstickdiva wrote:
@Wsmom wrote:I am also a sufferrer of UTIs and an Ellura user and always looking for something cheaper though afraid to switch. I looked up comparisons on treatments and found this article explaiining the difference between D-Mannose and cranberry. This is from "Review: Pac 36 supplements: Ellura, UTIVA or Theracran for UTI?" Uquora isn't included but maybe one of those is an equal comparison. Anyway, I found it an interesting read.
"#3 Is D-Mannose Better Than Cranberry For UTI Prevention?
When considering PAC cranberry products for UTI versus D-Mannose for UTI, it’s important to understand how both supplements work.
UTI starts because pathogenic bacteria (in most cases, E.coli) attach to the bladder lining in the way that it is impossible to simply pee them out.
E.coli can attach to the bladder through 2 different types of pili or “finger-like” projections called P-pili or type 1 pili. Think about pili as tiny tentacles that bacteria use to attach to your bladder lining.
P-pili is more virulent because it tends to cause kidney infections (p for pyelonephritis) while type 1 is less virulent and only causes bladder infections.
D-mannose actually attaches (or binds) to the type 1 pili so the E. coli is flushed out with the D-mannose. So, basically, E. coli grabs on to D-Mannose instead of the naturally occurring mannose on your bladder wall. And, since their “hands” are full of D-Mannose, they lose the ability to attach to the bladder lining.
On the other hand, cranberry blocks both type 1 and P-pili from attaching to the bladder wall (likely through a structural change), so the E. coli is peed out. We think that PAC-A somehow disables the tentacles of the bacteria from working and bacteria could not attach to anything anymore."
@Wsmom , I cannot stop laughing. I read this as tiny testicles and was like what? ROFLOL
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