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Re: Diabetes News 2020 winter

y Ben Fuchs | Pharmacist Ben

I’ve gotten a few questions lately about this stuff called Ezekiel Bread, which a type of bread that’s made largely from grains and beans that have been sprouted. The entire ingredient deck from this particular form of bread includes various organic sprouted grains (wheat, barley, spelt and millet), something called organic malted barley (which acts as a source of sugar and is used to feed by beer brewers to feed yeast), sprouted beans (soy and lentils), water, yeast and salt, Ezekiel bread is named for the prophet Ezekiel, who in the bible was given a recipe for making bread. Ezekiel 4:9 says: “

Ezekial BreadIt cannot be argued that sprouted breads are healthy choices when compared to regular bread. The minerals in the grains are more available to the human digestive system and they contain more protein. But that does not mean that these types of bread are overall healthy foods, especially if you have sugar problems.

The difference between sprouted breads and regular bread is mostly in the fact that while the latter is made from wheat flour, which is ground up wheat kernels, sprouted bread, is made from wheat kernels that have already sprouted. Because sprouts use up the sugar in the wheat kernels to make protein, Ezekiel bread has less sugar and more protein. But, because the kernels are typically not sprouted all the way, there is still sugar in Ezekiel Bread, not as much as there is in regular bread perhaps, but unless the kernel is completely sprouted and there is nothing left but the shell, you are still getting sugar. Just check out the nutritional facts that are printed right on the label. Every slice of Ezekiel Bread has 15grams or three teaspoonful of sugar in it. And most people are eating 2 or 3 slices. That means you’re looking at 6 teaspoonfuls of sugar if you’re eating a couple of slices. If you eat 3 or 4, that’s 9 to 12 teaspoonfuls of sugar. It’s not ordinary “table sugar”, its starch but it’s still going to get turned into sugar in your body, and it will raise blood sugar and create an insulin response.

One of the most obvious red flags when it comes to sprouted breads like Ezekiel Bread is that fact people really like it! And what is it that makes Ezekiel Bread such a popular alternative among the blood-sugar -conscious folks who try it? It’s probably not the fat because there’s only about ½ a gram of fat per slice of the stuff. And it’s probably not the protein, because there’s isn’t a lot of protein either. There’s a little fiber, but people don’t exactly go crazy about fiber. And you don’t see a lot of folks going out looking for sprouted barely or millet either. The reason people like Ezekiel Bread is the same reason people like most of the foods they eat. It’s the carbs! And the carbs in this sprouted bread are the same as the carbs in any kind of bread, (although the fiber, can slow down the release of the sugar).

Any way you describe it, the facts it is carbohydrates mean sugar! An average slice of white bread has around 20-25 calories, but an average slice of Ezekiel bread has 80 calories. There are over 3 times more calories in a slice of Ezekiel bread then there is a slice of white bread. And these are sugar dense calories. In fact NOT including the fiber (which is non-caloric), almost half the calories from Ezekiel Bread come from carbohydrates/sugar. It may not be pure sucrose or table sugar. It may be in the form of starch, but it will still have an effect on your blood glucose. 3 teaspoonfuls of sugar per slice! Ezekiel bread does have some protein value, so it’s not as bad as white bread or cake or pasta, which are awful and empty foods, but it’s still a load of sugar; sugar that you don’t need.
This is why we have to be savvy, why we have to be nutrition label readers. No one can deny that sprouted breads are better that regular bread, but if you are diabetic or concerned about blood sugar I’d avoid them. And, if you have leaky gut problems or Celiac Disease, or any digestive issues, it important to recognize that sprouted bread still contain gluten and allergenic proteins.

Sprouts are great, but Ezekiel Bread isn’t sprouts and it doesn’t taste anything like sprouts In fact it looks and smells and tastes like bread. A heavy, thick somewhat unusual bread but a “bread” nonetheless.

If we’re having blood sugar problems, and we know we should be getting off the bread, we’re kidding ourselves if we think the solution is to start eating a different type of bread, Ezekiel or otherwise. What we should be attempting to do is wean ourselves off of the bread habit and the bread taste. I’m not beating up on Ezekiel or any other sprouted bread. I’m just saying let’s not be fooling ourselves. Look on the nutrition facts. If it’s says carbohydrates, that means sugar and that means elevation in blood glucose and insulin and that means beware if you’re a diabetic or pre-diabetic. There’s just no other way you can slice it.

 
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Re: Diabetes News 2020 winter

mart Insulin Patch Could Revolutionize Diabetes Treatments

Published: Feb 05, 2020 By Alex Keown


smart insulin device under development could revolutionize how glucose levels are monitored in diabetes patients and deliver insulin doses when necessary.

Researchers from University of California, Los Angeles (UCLA), the University of North Carolina and Massachusetts Institute of Technology (MIT) are working on an adhesive patch, about the size of a quarter, and are planning to take their device and move it into human studies soon. The scientists have published their preclinical research conducted on mice and pugs in Nature Biomedical Engineering. A statement from UNC notes that the research team is seeking approval from the U.S. Food and Drug Administration to advance the study into human trials.

Zhen Gu, a professor of bioengineering at the UCLA Samueli School of Engineering, said in a statement that the goal of the project, which began in 2015, is to “enhance health and improve the quality of life for people who have diabetes.” The patch is intended to remove the need for diabetes patients to constantly check their blood sugar levels and then take insulin when needed. Gu said the patch “mimics the regulatory function of the pancreas” but remains easy for patients to use.

The experimental patch monitors glucose levels and has doses of insulin pre-loaded in micro-needles. The microneedles are made with a glucose-sensing polymer that's encapsulated with insulin. Each microneedle penetrates about a half millimeter below the skin, which is sufficient to deliver insulin into the body. When applied, the microneedles penetrate under the skin and can sense blood sugar levels. As the researchers describe, when glucose levels reach a certain threshold, the insulin is released. When the blood sugar levels return to normal, the insulin delivery slows. The researchers said this is designed to ensure there is not an overdose of insulin, which can lead to hypoglycemia, seizures, coma or even death.

In the experiments, one quarter-sized patch successfully controlled glucose levels in pigs with type I diabetes for about 20 hours, the researchers said. The pigs weighed about 55 pounds on average.

John Buse, director of the UNC Diabetes Center, said having an insulin-delivery device in a “smart and convenient manger” has always been a dream.

“This smart insulin patch, if proven safe and effective in human trials, would revolutionize the patient experience of diabetes care,” Buse said in a statement.

If the FDA accepts the application to begin testing the patch in humans, the research team said trials could begin within the next few years. The team believes that the smart microneedle patch could be used beyond diabetes. The researchers believe it could be adapted with different drugs to manage other medical conditions as well.

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Re: Diabetes News 2020 winter

n a pair of related studies, a team of Yale researchers has found a way to reverse type-2 diabetes and liver fibrosis in mice, and has shown that the underlying processes are conserved in humans.

The studies appear in the Feb. 4 edition of Cell Reports and in the Jan. 17 edition of Nature Communications.

In the earlier study, researchers found an important connection between how the body responds to fasting and type-2 diabetes. Fasting “switches on” a process in the body in which two particular proteins, TET3 and HNF4a, increase in the liver, driving up production of blood glucose. In type-2 diabetes, this “switch” fails to turn off when fasting ends, as it would in a non-diabetic person.

Researchers hypothesized that if they could “knock down” the levels of these two proteins, they could stop diabetes from developing. Yingqun Huang, M.D., Yale associate professor in Obstetrics, Gynecology, and Reproductive Sciences and her team injected mice with genetic material known as small interfering RNAs (siRNAs) packaged inside viruses that targeted TET3 or HNF4a. They found that blood glucose and insulin dropped significantly — effectively stopping diabetes in its tracks.  

In the Feb. 4 Cell Reports study, researchers looked at how TET3 contributed to the development of fibrosis in the liver, and found that the protein was involved in fibrosis on multiple levels. Almost all fibrosis, regardless of the organ involved, starts from abnormal protein signaling, Huang said.

She and colleagues discovered that TET3 plays a role in the fibrosis signaling pathway in three different locations — and acts as an important regulator in fibrosis development. This means there are likely opportunities to develop drugs that inhibit TET3 to slow or reverse fibrosis, said Da Li, associate research scientist in genetics and co-author on both studies.

Both diseases — type-2 diabetes and fibrosis of the liver and other organs — are common, but have few treatment options. Around 28 million people in the U.S. have type-2 diabetes, characterized by high blood sugar levels, a condition that can lead to many other health problems, including heart disease, stroke, and kidney failure.

Cirrhosis is one of the leading causes of death worldwide and is marked by liver fibrosis — a buildup of scar tissue on the liver, said co-author James Boyer, M.D., professor and emeritus director of the Yale Liver Center.

Researchers noted that several drugs, such as metformin, are currently available to control blood sugar levels in patients with diabetes. But these have a range of unpleasant side effects, and patients can develop resistance to these drugs.

And there is little medical relief for fibrosis sufferers.

Right now, there are no effective drugs for the treatment of fibrosis,” said Xuchen Zhang, M.D., associate professor in pathology and co-author on the fibrosis study.

Huang has filed for a patent related to her discoveries with support from the Yale Office of Cooperative Research.

The next step, she said, will be to identify where to best target TET3 and HNF4a and to develop the most effective siRNAs or small molecules to treat type-2 diabetes or fibrosis.

Both studies were supported by the National Institute of Diabetes and Digestive and Kidney Diseases at the U.S. National institute of health

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Re: Diabetes News 2020 winter

News
Initial trials show ‘revolutionary’ insulin patch works


By Mike Watts
Posted on 7th February 2020

il
An insulin-delivery patch which could “revolutionise” the lives of people with type 1 diabetes is one step closer to becoming a reality.

American researchers have come together to develop an adhesive patch which reacts to glucose levels and delivers the right dose of insulin.

The patch, about the size of a coin, has been accepted by the US Food and Drug Administration’s Emerging Technology Program.

The next step for researchers is to get approval to trial the technology in humans. This follows a series of successful studies, the most recently of which showed the patch helped control glucose levels in pigs for up to 20 hours.

Professor Zhen Gu, from the University of California, Los Angeles (UCLA) Samueli School of Engineering, said: “Our main goal is to enhance health and improve the quality of life for people who have diabetes.

“This smart patch takes away the need to constantly check one’s blood sugar and then inject insulin if and when it’s needed. It mimics the regulatory function of the pancreas but in a way that’s easy to use.”

The technology behind the patch involves lots of tiny microneedles pre-loaded with insulin. They deliver the hormone when needed and when blood sugar returns to normal, the patch’s insulin delivery also slows down.

Study co-author Dr John Buse, director of the University of North Carolina’s (UNC) Diabetes Center and the North Carolina Translational and Clinical Sciences (NC TraCS) Institute at the University of North Carolina at Chapel Hill School of Medicine, said: “It has always been a dream to achieve insulin-delivery in a smart and convenient manner.

“This smart insulin patch, if proven safe and effective in human trials, would revolutionise the patient experience of diabetes care.”

It is thought the patch could also be used to treat other conditions as the needles could be loaded with other medications.

Co-author Dr Robert Langer, from the David H. Koch Institute, added: “I am glad the team could bring this smart insulin patch one more step close to reality, and we look forward to hopefully seeing it move forward to someday help people with diabetes.”


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Re: Diabetes News 2020 winter

Type 1 diabetes could be tackled by a radical technique involving injecting insulin-producing cells into the eye


• It's found to cut need for regular daily insulin shots by more than half in animals
• Type 1 diabetes is caused by immune system destroying insulin-producing cells 
• In a new trial, patients will have donor cells injected into anterior chamber of eye
By Roger Dobson for the Daily Mail

Published: 19:30 EST, 3 February 2020 | Updated: 19:54 EST, 3 February 2020



 
 
Type 1 diabetes could be tackled by a new technique that involves implanting insulin-producing cells into the eye.

This has been found to cut the need for regular daily insulin shots by more than half in animals, and is now to be tested in humans.

While type 2 diabetes is linked with lifestyle and occurs when the body makes insufficient insulin — the hormone that mops up sugar in the bloodstream — type 1 is caused by the immune system destroying insulin-producing cells in the pancreas known as islet cells. 

There's no cure and patients require multiple doses of insulin by injection or pump every day.


+4
Type 1 diabetes could be tackled by a new technique that involves implanting insulin-producing cells into the eye (file image) 

Some patients are offered a transplant of insulin-producing cells into the liver, which can potentially cut the need for insulin altogether. 

 

However, even with anti-rejection drugs, the cells come under attack, and one trial at the University of British Columbia in Vancouver reported that half the cells were lost within days. The immune-suppressing drugs needed to limit such attacks can also cause side-effects, such as an increased risk of infections and cancer.

In a new trial, patients will have donor cells injected into the anterior chamber — the fluid-filled space between the iris (the coloured part of the eye) and the inner surface of the cornea at the front. This area has been chosen as it has 'immune privilege', meaning it does not launch an immune attack on foreign bodies, so the hope is that the transplanted cells won't be targeted.

The eye is one of the only areas in the body with immune privilege and it's thought this protects vision from the damage that may occur with swelling and inflammation that accompanies an immune response.

In the trial at the Bascom Palmer Eye Institute in the U.S., ten patients with type 1 diabetes who are blind in one eye will have islet cells donated from cadavers infused into their eye through a tiny incision in the cornea. The procedure, done under anaesthetic, takes about 25 minutes.


+4
In a new trial, patients will have donor cells injected into the anterior chamber — the fluid-filled space between the iris (the coloured part of the eye) and the inner surface of the cornea at the front (file image) 

Patients will be monitored for six months to check how the treatment affects their insulin needs and whether symptoms and blood sugar levels have improved.

(The participants are all on anti-rejection medication having also had kidney transplants — but researchers hope to ultimately demonstrate the need for little or none of these drugs.)

Several animal studies have shown the procedure can be highly effective. When doctors at the Bascom Institute and Miami University transplanted cells into the anterior chamber of the eye of a baboon with diabetes, the animal's own insulin production increased after three months, while the need for external insulin dropped by 60 per cent. Its eyesight was unaffected.

Commenting on the research, Dr Ali Aldibbiat, a consultant in diabetes and endocrinology at the Dasman Diabetes Institute in Kuwait and honorary research associate at Newcastle University, says islet transplantation has been increasingly used over the past two decades.

He adds: 'We eagerly wait for the result of the trial to see if this transplantation approach is safe for the eye and whether the transplanted islets are effective in treating diabetes.'

R

• A drug approved to treat type 2 diabetes can also help those with type 1, according to researchers in the U.S. 
Tablets of sodium-glucose cotransporter-2 inhibitors work by helping the kidneys lower blood glucose levels. 

In a study at the Cleveland Clinic Foundation involving 26 patients with type 1 diabetes, and reported in the Journal of Primary Care & Community Health, researchers found most of them had improvements in average blood sugar levels and in weight. 

 

Researchers believe it could be a 'useful' add-on treatment. 

 

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Re: Diabetes News 2020 winter

Killing cells from inside the duodenum of the small intestine could help control blood sugar levels among those with type 2 diabetes, researchers have said.

A US team say previous studies have shown that carrying out a procedure known as a DMR could help to lower HbA1c levels and manage type 2 diabetes.

DMR stands for Duodenal Mucosal Resurfacing, and involves using a catheter to deliver a balloon filled with extremely hot water (around 80 degrees Celsius) to the duodenum.

The duodenum is located between the stomach and the middle part of the small intestine. It is thought this part of the stomach becomes enlarged and stops working properly when it is exposed to an unhealthy diet for a number of years.

The hot water is then directed to burn cells lining the duodenum, which are thought to grow back healthily.

To test whether this approach could make a significant difference to people with diabetes, five institutions in America are trialling the procedure.

Results are not yet available, but Professor Gregory Ginsberg, Professor of Medicine at the Hospital of the University of Pennsylvania said the previous research has made him hopeful that he is studying a “transformative” procedure.

He added, “This research is compelling because it harnesses the untapped potential of the luminal digestive tract in the management of health and disease. Moreover, it is provocative in its application of minimally invasive endoscopic therapy to treat a metabolic condition.”

This rejuvenating process resets hormone production within the intestine part of the organ, the lion’s share of which are linked to metabolism and related diseases.

DMR was largely inspired by gastric bypass surgeries that have had promising results for type 2 diabetes. Bypass surgery results in partially digested food bypassing the duodenum. Obese patients with type 2 diabetes who undergo bypass surgery have been reported to see improvement in diabetes markers even before weight loss occurs. This sparked interest in the role the duodenum plays in metabolism, and led to these DMR trials.

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Re: Diabetes News 2020 winter

 
 
 
Best Snacks to Tame Hunger When You Have Diabetes These four healthy foods keep you feeling full longer and reduce blood sugar spikes for people with diabetes.
 
 

Best Snacks to Tame Hunger

Growing up in the Chicago area, I was always under the impression that the cold winter months drove my hunger up. I did some digging into the research only to find out I was incorrect. Cold temperatures offer the potential to increase energy expenditure, but don't affect your hunger and satiety levels. This misunderstanding is what led me to investigate science-based evidence on which foods could help increase my levels of satiety and why.

(Getty Images)

Satiety, or a feeling of fullness after eating, holds an important place in both weight management and blood glucose level management for people with diabetes. For instance, we should feel full after eating a meal or snack. The body has a series of mechanisms that occur as we eat. The hypothalamus, a tiny area in our brains, regulates both our desire to eat and to stop eating. And there is a temperature component: When we eat, our body temperature increases, and we start to reduce the amount of food we're eating.

Taking a deeper dive into our body's mechanisms that relate to hunger versus satiety, I found these important identifiers. Foods that will be highly satisfying – and also filling – include:

  • Foods high in fiber, low in energy (calories), high in protein and high in volume (large portion size but low in calories).
  • Taste, smell and texture also play a role in level of satiety. For instance, the chewier a food – or the more chewing required – the greater feeling of satiety it offers.

Higher fiber foods add bulk to your diet, which helps increase satiety, as well as prolong that full feeling longer than other foods. For people with diabetes, higher fiber foods serve as an added benefit by helping slow down the absorption of carbohydrates. Foods that contain protein have been shown to increase satiety due to changing the levels of some satiety hormones.

Almonds vs. Crackers


A recent study published in Nutrients compared snacking between breakfast and lunch on a small serving of raw almonds versus a comparable serving of savory crackers. Essentially the study found that participants who snacked on almonds before lunch exhibited overall lower hunger, a less subconscious desire to consume other high-fat foods and ate fewer calories at lunch. And, of course, from my view as a diabetes care and education specialist and a person with diabetes, for diabetes management, the almonds contained only about one-quarter the carbohydrates of the crackers.

For example, my individualized snack, had I been a participant, would have been about 2 ounces of the snacks with 18 grams carbohydrate (crackers) or less than 5 grams carbohydrate (almonds). This is good news for people with diabetes. Consuming almonds as a snack versus crackers can reduce blood sugar rises due to the makeup of nuts, which are a lower-carb, high-fiber food choice.

 
Avocado


Hungry for more foods that can offer you satiety? A randomized crossover study involving healthy overweight participants looked at the effects on satiety, insulin levels and blood sugar response when one half of an avocado was added to the lunch meal. The results were positive just like the almond study. Avocado, which is high in fiber and low in carbohydrate, meets the profile of foods that will likely offer satiety.

Dark Chocolate


Dark chocolate is also on the list of satiety boosters. We are talking dark chocolate as in over 85% cacao – yes, the bitter chocolate, not the Halloween candy. Bitterness has been shown to reduce appetite and offer the feeling of fullness attributed to the stearic acid in the dark chocolate. There's also evidence that even smelling dark chocolate can elicit satiety. Yes please, but you will want to make sure to include the 1-ounce serving in your carbohydrate allotment.

Decaf Coffee


Choose coffee, preferably decaf, as your beverage when you are feeling a hunger pang. There have been several studies showing a decrease in hunger and increase in satiety levels for a three-hour period after a cup of decaf was consumed. How did this happen? The research showed there was an elevation in a gut hormone that resulted in satiety.

It's important to me that the characteristics of foods that help us feel fuller (satiety) also fall into the category of healthy food choices for people with diabetes. It's a win win. Foods that are high in fiber and contain a combination of complex carbohydrate, lean protein and healthy fat, will help balance blood sugar and make us feel fuller longer. Plus, a winter snack of almonds, dark chocolate and coffee sounds pretty tempting.

Best Diabetes Diets

DIET Ranking information as of January 29th, 2020

 
 

Toby Smithson, Contributor

Toby Smithson, MS, RDN, LD, CDE, began writing for U.S. News & World Report in 2016, covering ...

 
 
 
 
 
 
 

 

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Re: Diabetes News 2020 winter



Health News

New Treatment Could Help Diabetes Patients Achieve Remission

New procedure encourages cell growth and spurs the pancreas to produce insulin once again in some people.

Researchers are working on new treatments that could help some people living with diabetes avoid insulin injections. Getty Images
A new treatment that encourages cell growth may have the potential to put diabetes into remission in some patients.

Researchers have outlined the new procedure in a study recently published in Diabetes Care.

The researchers have been looking at a process that involves regrowing the cells on the surface of a patient’s small intestine.

These new cells then spur the pancreas to produce adequate amounts of insulin again.

This could allow many with type 2 diabetes who are taking oral medications to avoid insulin injections as well as put their disease into remission.

This promising new treatment — known as “duodenal mucosal resurfacing” — involves inserting a thin tube with a small balloon attached to one end through a sedated patient’s mouth and into the stomach.

The tube is then positioned at the top of the small intestines, at which point the balloon is filled with hot water.

The heat from that hot water destroys the endothelial cells on the surface of the small intestines — a technique called ablation therapy.

This then encourages the growth of new healthy cells and improves the patient’s ability to produce insulin.


How the treatment works

While it’s early in the ongoing observation of the results, this method has been effective for more than one year after study participants first received treatment.

That’s because the lining of the small intestines is largely responsible for the production of insulin.

After food is digested in the stomach, it travels to the small intestine, where glucose produced from that food is absorbed into the bloodstream.

This process signals the pancreas to produce insulin. That insulin helps transport the glucose into every area of the body that relies on it.

Without enough insulin, glucose builds up in the bloodstream.

That’s what leads to dangerously high blood sugar levels that damage the nerve endings and blood vessels throughout the body, including those in the eyes, fingers, and toes.


Quick improvement

The results of this new procedure were similar to that of patients who have received gastric bypass surgery.

Researchers said there was improvement in blood sugar levels for study participants within a few days and weeks.

This improvement happened regardless of diet or weight loss.

“Contrary to common perception of type 2 diabetes, they’ve found that low insulin production is a major factor for most people with type 2 diabetes, not insulin resistance,” explained Gretchen Becker, medical journalist and author of “The First Year: Type 2 Diabetes.”

Becker told Healthline that most patients with type 2 diabetes have varying degrees of insulin resistance, but so do people who don’t have diabetes.

While the bodies of those in the latter category simply produce more insulin to compensate, a person with type 2 diabetes doesn’t seem to be able to.

“Most genes related to type 2 diabetes concern insulin production, not insulin resistance,” Becker said.

She added this contributes to why the ablation of the small intestines’ lining has proven to be so effective in normalizing patients’ ability to maintain healthy blood sugar levels.


Dr. George Grunberger, FACP, FACE, the founder of the Grunberger Diabetes Institute in Michigan, told Healthline he is excited about the results of this procedure and others like it.

“Quite a few years ago, in Chile, a similar procedure was being studied that involved inserting a balloon into the small intestines to act as a lining, so the food never touched the wall during digestion,” explained Grunberger.

“Consequently, the patients’ blood sugar levels regulated themselves, simply by interrupting and preventing that interaction with the mucosal lining.”

Ever since, Grunberger said everyone has been trying to convince the Food and Drug Administration (FDA) about the safety of this type of procedure.

“If you catch people early in the game of diabetes,” explained Grunberger, “you can put diabetes into remission by renewing or blocking the interaction with the lining of the small intestines, but for how long? We don’t know yet.”

In his own practice, Grunberger sees an 80 to 95 percent success rate in achieving diabetic remission through traditional gastric bypass or gastric sleeve procedures.

Both of these procedures involve removing or limiting contact with a certain portion of the small intestines.

“These types of procedures have proven to improve glucose tolerance virtually immediately,” he explained. “This means it isn’t the result of calorie restriction or weight loss, but in merely interrupting that normal interaction with the mucosal lining.”

That being said, those who maintain remission in the long term are still those who are able to successfully lose weight and sustain it.

“I have patients who have undergone gastric bypass who were on insulin for years prior to surgery,” explained Grunberger. “They don’t need insulin anymore, they maintain an HbA1c of 5.2 percent, and they come back every year just to say, ‘Hi.’”

Grunberger also has patients who don’t change their habits and regain most of the weight. But even then, many of them are able to use other diabetes medications instead of going back to insulin injections.

The real hurdle this study — and those like it — will have to overcome is demonstrating not only its safety but also its long-term efficacy.

If a patient’s success after duodenal mucosal resurfacing only lasts for a few years, it’s unlikely insurance companies would be willing to pay for it.

Ginger Vieira is an expert patient living with type 1 diabetes, celiac disease, and fibromyalgia. Find her diabetes books on Amazon and connect with her on Twitter and YouTube.


Written by Ginger Vieira on November 12, 2018

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Re: Diabetes News 2020 winter

One step closer to fixing diabetes...from Mt Sinai Hospital

 

 

https://www.youtube.com/watch?v=IShN945e5CI&feature=youtu.be

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Re: Diabetes News 2020 winter

[ Edited ]

I popped in just to share this. I feel it is important. I will be gone for  the Lenten season until it  is over and return ater Easter. I might pop in for a Sunday because Sundays are not included in the fast. They are all technically all Easter, but I am not sure. I you have any question @Trinity11 is a person who can help you. She ws an instructor for diabetic groups, so you can trust what she tell you

 

I want to encourage everyone to stick to you food plan, and remember you get to decide  when and if you are givng yourself a treat. Ignore those who decide to make what you eat their business

 

We all eat something we shouldn't on occasion..try to limit your portion . I always share a goody with Mr Cherry, and let him have the lions share, but do what works for you

 

As for Avandia talk to your Dr first ,and your pharmacist, before you decide on anything

 

 

 

 

 

Avandia

 

 

 

33% higher risk of cardiovascular disease

The analysis revealed a 33% higher risk of heart attack, heart failure, cardiovascular deaths, and noncardiovascular-related deaths combined for people who were taking the drug compared with people who were taking another control substance, including placebo.

Wallach and colleagues conclude:

“The results suggest that rosiglitazone is associated with an increased cardiovascular risk, especially for heart failure events.”

The findings also serve to emphasize the importance of using raw data to accurately assess the safety of a drug, say the authors.

“Our study suggests that when evaluating drug safety and performing meta-analyses focused on safety, IPD might be necessary to accurately classify all adverse events,” they write.

“By including this data in research, patients, clinicians, and researchers would be able to make more informed decisions about the safety of interventions.”

“Our study highlights the need for independent evidence assessment to promote transparency and ensure confidence in approved therapeutics, and postmarket surveillance that tracks known and unknown risks and benefits.”