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During today's shows, Andrew Lessman shared a lot of information on CoQ10.

 

I dictated as much of this information as possible on my laptop. I haven't had the opportunity to proof read it yet, but I thought I'd go ahead and share my rough copy of information. It's divided into three sections: 

 

* Andrew's general charts on CoQ10

 

* Andrew's quotes from Scientific & Medical journals on CoQ10

 

* Andrew's general observations on CoQ10

 

Enjoy!! 

 

-- bebe Smiley Happy

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Re: CoQ10 - Coenzyme Q-10

[ Edited ]

 

 

Coenzyme Q-10 200mg. — Andrew’s general charts

 

 

 

Functions exactly like an essential and protective vitamin. 

 

* Most people don't realize that COQ10 would be the most important vitamin — though it’s technically not a vitamin — if our body didn't have the ability to make a small amount of it. Because our body can make a small amount of it, it's technically not a vitamin. But, as we get older, our body makes less and less and so CoQ10 becomes the most important “vitamin” that our body needs to supplement along with vitamin D.

 

Required for ALL life and ALL cellular energy production.

 

Must be present in ALL living cells or they cannot produce energy.

 

* In other words, without CoQ10, these cells will not be alive.

 

Reduced levels are a natural result of aging, stress, poor diet, smoking, consumption of alcohol and drugs; and contribute to fatigue.

 

  • As our levels get suppressed in terms of COQ10 synthesis it contributes to fatigue.

 

Essential for the production of ALL energy for ALL metabolic work within ALL cells, tissues and organs.

 

  • if you want your key organs to function the best, you have to have adequate levels of CoQ10.

 

Our vital organs require a constant supply of energy, and CoQ10 is required to keep them functioning their very best.

 

The highest levels of CoQ10 are found in the most vital organs: heart, brain, liver, kidneys, lungs and pancreas.

 

There are approximately 100 trillion cells in human body (100,000,000,000,000).

 

Each of those cells relies on as many as 1,000 mitachondria to use its CoQ10 to produce all that cell’s energy.

 

The Result: as many as one hundred quadrillion (100,000,000,000,000,000) mitochondria in our bodies rely on CoQ10 to produce ALL our energy.

 

  • COQ10 is what drives energy production in mitochondria.

 

  • The energy we have is a byproduct of the electron transport in the trillions and trillions and trillions of cells in your body that is taking place in the electron transport mechanism of the mitochondria of those cells and that’s what COQ10 does. 

 

  • We eat food and the food becomes fuel, yes we breathe and the oxygen is necessary for the oxidation terms of energy production that takes place within our body but ultimately the movement of these little tiny electrons determines the energy with which we experience life. And that experience of energy is a result of the movement of electrons that is precipitated (caused) CoQ10.
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Re: CoQ10 - Coenzyme Q-10

[ Edited ]

 

 

Coenzyme Q-10 200mg. — Andrew’s general charts (cont.) 

 

 

 

COQ10 levels and our body’s production of CoQ10 decrease with:

  • Age
  • Stress
  • Poor Diet
  • Fatigue
  • Smoking
  • Exercise
  • Illness (Diabetes, Liver, Heart, etc.) 
  • Alcohol Consumption
  • Cholesterol-Lowering Statin Meds, Osteoporosis Meds (bisphosphinates), Antidepressants, High Blood Pressure (Beta Blockers) and other Drugs.

 

  • With those suffering from depression, they frequently find lower CoQ10 levels.

 

Helps to support and maintain:

  • Normal blood pressure.
  • Normal cholesterol levels.
  • Normal blood sugar levels.
  • Normal triglyceride levels.

For those already in the normal range.

 

* COQ10  affects the energetics of so many systems in our body that help keep those levels at the normal range. It's a tool that helps us keep what we struggle to achieve.

 

The body must replace 500 mg of CoQ10 that is lost each day.

 

* When we're young it's not a problem but, in our thirties, fourties and fifties, it becomes the problem.

 

Our body’s only source of CoQ10 is food, supplements or internal production.

 

Animal organs and meat are, by far, the richest source of CoQ10; however, a diet rich in meat and fish only delivers 3-6 mg daily.

 

Therefore a supplement has become the most reliable source of CoQ10.

 

COQ10 helps to support and maintain:

  • Fragile, highly sensitive tissues of the gums and mouth.
  • Delicate, complex tissues of the Brain, Liver, Lungs and Kidneys.
  • Optimum Immune, Nervous and Cardiovascular System Function.

 

  • COQ10 is responsible for maintaining those tissues because it is responsible for the energy involved in maintaining those tissues.

 

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Re: CoQ10 - Coenzyme Q-10

[ Edited ]

 

Coenzyme Q-10 200mg. — Andrew’s general charts (cont.) 

 

 

 

CoQ10 levels in key foods:

  • Pork Shoulder – 4 ounces – 5.1 mg
  • Beef Shoulder – 4 ounces – 4.5 mg
  • Chicken Thigh – 4 ounces – 2.8 mg
  • Canned Tuna – 4 ounces — 1.8 mg
  • Chicken Breast – 4 ounces —1.4 mg 
  • Chicken Wing — 4 ounces —1.3 mg
  • Salmon – 4 ounces – .68 mg
  • Milk – 8 ounces – .438 mg
  • Shrimp – 4 ounces – .26 mg
  • Eggs -– 2 eggs — .22 mg

 

  • The best CoQ10 levels come from meat or animal products by far. You can see from the above chart that, effectively, there's no good dietary source of CoQ10. Pig Heart is a better source but, even then, you're only getting a few milligrams more CoQ10.
  • The highest levels (concentrations) of CoQ10 in your body are in your heart, liver and brain.
  • COQ10 Levels: If you're a vegetarian it's very healthy, but you're only getting nominal levels of CoQ10.
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Re: CoQ10 - Coenzyme Q-10

[ Edited ]

 

 

COQ10 — Medical Journals

 

 

 

Studies demonstrating the benefits and importance of CoQ10 have been published in the following Scientific and Medical Journals: 

 

Clinical Biochemistry

 

Nutritional Sciences

 

Journal of the American College of Nutrition

 

International Journal of Tissue Reactions

 

Current Neurovascular Research

 

Free Radical Biology & Medicine

 

Experimental Gerontology

 

Regulatory Toxicology and Pharmacology

 

American Journal of Cardiovascular Drugs

 

British Journal of Clinical Pharmacology

 

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Re: CoQ10 - Coenzyme Q-10

[ Edited ]

 

 

CoQ10 — Medical Journals (cont.)

 

 

 

Current Neurovascular Research

 

“fatigue is the seventh most common symptoms in primary healthcare."

 

"fatigue is defined physiologically as the inability to maintain the expected power output.”

 

 

Current Neurovascular Research

 

"it was reported that animals supplemented on Coenzyme Q may reach a significantly longer mean lifespan (11.7% higher), a significantly higher maximum lifespan (24% higher) and increased learning capacity than non-supplemented animals, suggesting that a long-term supplementation with a small dosage of Coenzyme Q-10 may represent a good anti-aging therapy.”

 

 

Current Neurovascular Research

 

"There is evidence that mitochondrial dysfunction and oxidative stress are directly related to fatigue in humans.”

 

* mitochondria are the powerhouses that make energy within our cells.

 

"Thus, enhancement of mitochondrial functions with Coenzyme Q-10 may be an important mechanism by which fatigue can be reduced.”

 

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Re: CoQ10 - Coenzyme Q-10

[ Edited ]

 

 

CoQ10 — Medical Journals (cont.)

 

 

 

 

Reviews in Food Science and Nutrition

 

"the human body biosynthesizes CoQ10, but it's endogenous tissue levels drop progressively with increasing age."

 

“Coenzyme Q-10 is chiefly found in the most active organs like the heart, kidney, and liver, where and even greater decline can be served with increasing age.”

 

 

Reviews in Food Science and Nutrition

 

"the intracellular biosynthesis of CoQ10 begins… through a cascade of [amino acid] precursors which indispensably require eight vitamins, namely – vitamins B6, see, B2, B12, folic acid, niacin, and pantothenic acid.”

 

 

American Journal of Cardiovascular Drugs

 

“HMG – CoA reductase inhibitors (statins), the best selling prescription drug class in the US. Include atorvastatin [Lipitor}, the best selling prescription drug in the world.”

 

 

American Journal of Cardiovascular Drugs

 

“statins inhibit the enzyme H and G – COA reductase, at a stage early in the mevalonate pathway. This pathway generates a range of other products in addition to cholesterol, such as co-enzyme Q-10…”

 

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Re: CoQ10 - Coenzyme Q-10

[ Edited ]

 

 

CoQ10 — General Information that Andrew provides

 

 

 

Essential as CoQ10 is, we also make sure that you were getting all of the B vitamins that are responsible for energy production… riboflavin, FAD, NADH. These are the other things in your cells that are responsible for transporting electrons along with CoQ10. We make sure that you're getting these ingredients as well: B1, B2 ,B3, B5, B6, special protected B12 (not destroyed in the stomach), folic acid, biotin, and 300mg Vitamin C. — He includes these additional ingredients because the chain is only as strong as its weakest link. This allows CoQ10 to deliver on its energy promise.

 

For periodontal issues, CoQ10 is the most important nutritional supplement. This is because generally your teeth are not your weakest link, rather your gums are you weakest link. And CoQ10 helps support your gum health. — This has the best science, clinical studies and research behind it.

 

Is also important for eye health because CoQ10 is one of the most important antioxidants in the body.

 

CoQ10's ability to transport electrons within the cells to make energy, that same ability to move electrons is how it quenches free radicals to protect your cells from the oxidative damage that can be done by these free radicals.

 

CoQ10 comes in soft gel capsules that kind of look like an Omega-3 capsule. There's no reason to do this because CoQ10 (ubiquinone, versus ubiquinal) naturally exists in a dry powder form. All that putting it in a capsule does is to then require additives, solvents and emulsifiers. — The one thing that comes from viewing the science and clinical studies is that it doesn't make sense to compromise the quality of the CoQ10.

 

In terms of absorption, CoQ10 is easily absorbed if you take it with a meal that has a little bit of fat in it. Or do what Andrew does, and just take your CoQ10 at the same time as you take your Omega-3. So you don't have to adulterate the CoQ10 to make it well absorbed.

 

About 15 years ago, natural Kaneka CoQ10 (the worlds finest CoQ10) represented about 80% of the CoQ10 on the market. Since that time, Chinese CoQ10 has come to dominate the market. Andrew feels the Chinese CoQ10 is not as good as Kaneka CoQ10: it's not as pure and it's not as bio-identical. Currently Chinese CoQ10 has 80% of the total market share. — Andrew's company has never used any other CoQ10 besides Kaneka CoQ10.

 

Andrew is not aware of any other country (including in the USA), with the possible exception of Japan, that has offered CoQ10 for longer than he has. Andrew started offering CoQ10 in 1984.

 

You cannot find an ingredient that is more central to energy production in every single cell of our body than CoQ10. So rather than stimulating your nervous system and brain (e.g. energy drinks or caffeine), or rather than just loading in more calories, it makes more sense to go to the very system that determine energy and fatigue in our body: the electron transport system.

 

Fatigue has little to do with the energy we have sitting on our body, but it has everything to do with the small mechanisms on the small level of every single cell in the body that produces that energy.  — All of the energy produced in our body has to do with the transport of electrons. It is the transport of electrons that are taking place in the cells, And not even in the cells themselves but in the small organelles (these mini mini organ structure) called mitochondria in our cells. It is the transport of electrons that entirely determines whether you are alive, whether you have energy or if you are fatigued.

 

It is also one of the most powerful protective internal compounds. 

 

Much like a power plant makes energy, it also pollutes. What happens in our body is that CoQ10 makes energy but it also affects our body (by creating toxic, free radical electrons). — It makes sense that CoQ10 is central to energy production, but it also deals with the fallout from energy production.

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Re: CoQ10 - Coenzyme Q-10

[ Edited ]

 

 

CoQ10 — General Information that Andrew provides (cont.)

 

 

 

Much like a power plant makes energy, it also pollutes. What happens in our body is that CoQ10 makes energy but it also affects our body (by creating toxic, free radical electrons). — It makes sense that CoQ10 is central to energy production, but it also deals with the fallout from energy production.

 

Andrew does his CoQ10 TS in October because there is also a longer money back guarantee at this time of the year. Normally it’s 30 days, but now it’s close to 120 days (extended holiday return policy). 

 

Vitamin C works with CoQ10 to cycle itself (they help to recycle each other). They’re in sort of in antioxidant cycle and reduction cycle. So they work together to recharge one another (i.e. Vitamin C helps to recharge the CoQ10 in your body, and vice versa). Your body you can't make CoQ10 without Vitamin C. 

 

B vitamins are critical for energy production and you can't produce CoQ10 in your body without these critical B vitamins and especially B12. 

 

Coenzyme-Q10 is more than just an enzyme. It's a coenzyme meaning the enzymes in your body, which are responsible for energy production, can’t work without the coenzyme CoQ10 to transport electrons.

 

Andrew started talking about CoQ10 31 years ago, which was before it became available as a supplement (in 1984).

 

When it's in skin care products it's like fairy dust; they just put a tiny amount in there.

 

Our heart distributes oxygen around our body by pumping blood. Our heart distributes nutrients throughout our body by pumping blood. Our heart doesn't distribute energy. In fact nothing in our body distributes energy. — In our body, every single cell in our body cannot depend on any other cell, but is entirely on its own is energy production. Each cell in your body is responsible for its own energy production. And it must have CoQ10 or it is not transporting the electrons and not performing that work that is energy production. Without CoQ10 in each cell, those cells can't be alive because those cells can't transport energy. Each cell has the independent responsibility of creating energy or it dies.

 

ENERGY — The collective efficiency of trillions of cells in our body is what energy really is in its most fundamental and conscious center. This is what creates the consciousness we have of whether we're energetic or whether we're fatigued. — It's not caffeine for energy. It's not calories for energy. It's really the tools on the cellular level because every single cell must produce its own energy: their neighbors can't do it for them. They have to do it on their own. — As CoQ10 levels go down, your energy level goes down as well your body cannot feel energetic if it does not have to tools (i.e. CoQ10).

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Re: CoQ10 - Coenzyme Q-10

[ Edited ]

 

 

CoQ10 — General Information that Andrew provides (cont.)

 

 

 

11:45am ET— They are more than halfway through their entire quantity of CoQ10 for the entire day. And they are more than 60% through the quantity for the large 600 capsule size.

 

11:59am ET — 28,200 CoQ10 bottles sold.

 

Omega-3 fats (or any other healthy fat) provide a perfect springboard for the maximum absorption of CoQ10.

 

Kaneka CoQ10: 

  • they were the first to manufacture natural, bio-identical CoQ10 more than 30 years ago.
  • Only their CoQ10 has been approved for the National Institutes of Health (NIH) clinical studies.

 

80% of the CoQ10 that you will find in retail stores these days is Chinese CoQ10. Andrew does not feel did it is of the same quality as Kaneka COQ10.

 

CoQ10 is the primary component for electron transport which is how we experience all energy. B vitamins are also an integral part of that energy production process. Since a chain is only as strong as its weakest link, we also give you those B complex vitamins not only so that you can produce your own COQ10, but also because when CoQ10 goes to work it needs B complex as a partner to deliver its greatest energy benefits.

 

12:50pm ET — They are about two thirds of the way through all of their quantities of CoQ10.

 

 

UBIQUINONE vs, UBIQUINAL

  • Ubiquinone is one form of CoQ10 and the other form is ubiquinol. They interchange within your body. Ubiquinol is talked about as being the more active form. Andrew is not convinced of that. So he would rather have you purchase the less expensive ubiquinol and get more CoQ10 for your money. — Andrew suspects that Kaneka as well as other vitamin manufacturers would rather have you purchase the more expensive ubiquinol, but he thinks that ubiquinone is your best bet. For the past 30 years 90% of the clinical science has been on ubiquinone, Andrew doesn't see any reason to spend more and get less (i.e. ubiquinal).

 

Energy production is what determines how well our heart, liver, muscles, etc. can function.

 

The research talks about the fact that CoQ10 is rate determining in that it determines the rate at which the body can produce energy. And, as such, the rate at which or the degree to which our organs can function at their very best.

 

1:00pm ET — 32,635 bottles sold.