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12-19-2020 11:44 AM
You need to discuss dosing, and if CoQ10 is right for you, with your doctor. Dosing is based on individual needs. One dose doesn't fit all.
For example, I have a history of PVC's (since I was in my 30's) with any stimulants, such as caffeine, or decongestants, that type of thing. For some reason, when I take even lower doses of CoQ10, I have increased PVC's. So it seems to have a stimulant effect with me.
12-19-2020 12:02 PM - edited 12-19-2020 03:47 PM
I started taking Co-Q10 years ago and credit it with getting me out of the periodontist's chair. I think at that time I was taking 200, but switched to 100 when I started taking Qunol which is Ubiquinol and, therefore, absorbed better. I haven't had any deterioration in my dental health which was never good to begin with, but mostly now it's crowns not gum disease. I am now on a statin and my doctor does recommend taking it.
12-19-2020 01:24 PM
Ubiquinone is the same thing as CoQ10. Ubiquinol is the metabolite (broken down and bioavailable) form of ubiquinone.
12-19-2020 01:39 PM
@SilleeMee wrote:Ubiquinone is the same thing as CoQ10. Ubiquinol is the metabolite (broken down and bioavailable) form of ubiquinone.
@SilleeMee I see this listed on the TSV's ingredients....it says natural ubiquinone so at least his is the bioavailable kind.
Looking at a bottle of Qunol I tried from Costco a few yrs ago (got about 10 caps left!) says Mega CoQ10 UbiQuinol (the active form of CoQ10) Hmmm...back of label says Ubiquinol (hydrosoluble) 100mg's.
So Qunol main ingredient actually is the one that our bodies must first break down and convert into the active absorbed kind. Yet their bottle declares the opposite!
Good grief....LOL!
12-19-2020 01:48 PM - edited 12-19-2020 02:26 PM
@SilleeMee Went over to Costco's site....their store brand Kirkland and another brand Turnature have the active ingredient listed as Ubidecarenone. WHAT is that??
I know when I took the Qnol I felt nothing...no improvements or reactions just nothing.
I have fatigue issues and the correct form of CoQ10 would be best as it helps the body with ATP production which is the energy in the cells of our bodies.
Edit: just googled this!
12-19-2020 02:06 PM - edited 12-19-2020 02:17 PM
What I do know is that ubiquinone (CoQ10) is metabolized in the body by an enzyme we have in our body and what ends up is ubiquinol which is the absorbable (bioavailable) form of the coenzyme. Older people have far less of that metabolic enzyme required to metabolize CoQ10 so a lot of the CoQ10 goes to waste. Older people, or people with certain medical conditions, would benefit the most from ubiquinol and not so much from ubiquinone (CoQ10). In other words a person can take all the CoQ10 in world but if their body doesn't have what it takes to make it absorb then it's useless. What it takes is an enzyme which our bodies make naturally but as we age that enzyme level goes down.
12-19-2020 02:14 PM - edited 12-19-2020 02:21 PM
@SilleeMee wrote:What I do know is that ubiquinone (CoQ10) is metabolized in the body by an enzyme we have in our body and what ends up is ubiquinol which is the absorbable (bioavailable) form of the coenzyme. Older people have far less of that metabolic enzyme required to metabolize CoQ10 so a lot of the CoQ10 goes to waste. Older people, or people with certain medical conditions, would benefit the most from ubiquinol and not so much from ubiquinone (CoQ10).
@SilleeMee Ok I think I Have this all backwards! So AL's TSV and Kirkland/Trunature have the hard to process kind and the Qunol brand has the good easy to asorb kind??
Sorry I need it in simple to understand stuff LOL!
Do I have this right now??
From Wikipedia:
It is well-established that CoQ10 is not well absorbed into the body, as has been published in many peer-reviewed scientific journals.[4] Since the ubiquinol form has two additional hydrogens, it results in the conversion of two ketone groups into hydroxyl groups on the active portion of the molecule. This causes an increase in the polarity of the CoQ10 molecule and may be a significant factor behind the observed enhanced bioavailability of ubiquinol.
12-19-2020 02:20 PM
I'd have to look at the bottle. If it says it contains ubiquinol then that is the one older people should be taking. There is a big price difference between ubiquinone and ubiquinol. Ubiquinol is expensive.
12-19-2020 02:22 PM
@SilleeMee Thank you LOL....I just edited my post and put a wikipedia info quote on it which is helping me keep them straight!
12-19-2020 02:33 PM
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