I have a pair of Orthofeet. Very comfortable and they offer free s/h both ways. Having said that, I have found Jambu, Bzees and Easy Spirit to be equally comfortable and supportive--in some styles--at a much lower cost. Have not as yet bought another pair from Orthofeet.
I think if you have problems with your feet or are an unusual size, they may be worth a try. I know a good friend of mine buys many of his shoes from them because he is a big guy and does have problems with his feet.