Respected Contributor
Posts: 2,453
Registered: ‎05-02-2017


Yes, I agree with all the other posters--diabetes and kidney disease are usually the main issues for lots of water intake and accidents.


If it were a cat I might say that perhaps the pet has a hair ball, but not so much with dogs.


I have had pets with both diseases, and with treatment (insulin shots, diet, etc.) they can live for many years.


Usually it is older pets that are diagnosed with these, but depending on genetics and it the pet is overweight, the diseases can occur earlier.


However, I also had a cat once with similar symptoms, and he had cancer of the blood.


If your vet does not have the ability, go to a vet specialty hospital, and they can run a more comprehensive assessment than local vets. Yes, it costs a bit up front, but the peace of mind will be knowing the issue and how to (hopefully) treat it.


Best wishes!

Trusted Contributor
Posts: 1,351
Registered: ‎06-27-2010
@Puppylips. I had this exact thing happen and went through all of the same tests with one of our 9 year old terrier mix females. All diabetes, Cushings, Addisons and kidney tests with no causes. Our vet persevered and after 2 months came up with the answer. She has diabetes insipidus. Fortunately we have been treating her successfully with a medication named desmopressin which is inexpensive and easy to get at any pharmacy. We get it at stop and shop for about $14 per month. I hope your dog turns out to have nothing at all but considering everything we went through for months until we found out what it was, we were fortunate.
Esteemed Contributor
Posts: 6,996
Registered: ‎05-09-2010

@cjm61 wrote:

@Puppy Lips I have to say upfront, I really don't know that much about your dogs issue. My 2 cents worth, my brother's dog had the same symptoms and it turned out his Shih Tzu had diabetes. At that time I wasn't aware dogs could get diabetes. Has your little puppy been tested for that?

@cjm61 That was mentioned as a possibility.  It turns out the STEM test won't be done until next Friday because the Vet did not have enough of the drug.  So maybe that test will look for that.  So far they have not said that she did or did not have it.

Always remember that you are absolutely unique. Just like everyone else. Margaret Mead
Esteemed Contributor
Posts: 6,996
Registered: ‎05-09-2010

@FancyPhillyshopper She is a bit overweight.  If that brought this on then I will feel really bad. 


Our 15 year dog was losing weight rapidly.  She may have liver cancer based on her blood tests.  But we did not want to find out for sure due to her age, and the expense, though I never asked how much that would be.  Anyway, she is on a lot of meds and our goal was to keep her eating.  So she gets a mix of a lot of foods, some homemade, and she eats it all up and  stopped losing weight.  She is hanging in there.  She has already lasted longer than I thought.  She seems happy and not in any pain.  


So we are feeding our Husky mix the same food and treats.   She also does not get enough exercise because the 15 year old sometimes does not want to walk too far.  I am afraid in our quest to keep the older dog alive, we have not paid enough attention to our husky's condition.


I was so hoping this was something simple.

Always remember that you are absolutely unique. Just like everyone else. Margaret Mead
Valued Contributor
Posts: 651
Registered: ‎09-30-2012

@Puppy Lips I think you are very lucky to have a vet that seems to be on top of things.  When our first westie got sick our vet didn't know what was wrong.  He was just about to refer us to a specialist when his partner brought up addisons and he was right.  My vet probably wouldn't have tested for addisons without his partner.  When my second westie got sick he didn't know what was wrong again and I said "you don't think it is addisons, do you?"  He then tested and I was right.  He would have missed it twice since it's not real common.  It seems like your vet is on the ball.  He will figure it out.  If it is addisons it is important to keep their weight under control.  Let us know when you have an answer and best of luck.

Respected Contributor
Posts: 3,780
Registered: ‎07-18-2013

@Puppy Lips I have had Doxies with both Addisons' and Cushing's Disease.  Both required STEM tests and the last one (with Cushing's) had a STEM (or the shorter version) done about every month or so as he was very sensitive to prednisone and we had a lot of problems adjusting his doses of medications.  And yes, we also had another dog getting sub q injections and tests for a chronic bladder infection at the same time to adjust her medications.  

If my dog doesn't like you, neither do I.
Honored Contributor
Posts: 8,095
Registered: ‎10-03-2014

I had a dog with Cushing's snpiy 4-5 years ago, but the diagnosis did not cost nearly that much and the vet was a specialist in Internal Medicine.  


Does your dog pant a lot, look overweight, particularly in the abdominal area?  Both symptoms can be Cushing's.  


Yes, my very large Standard Poodle was on medication for the rest of his life.  He was 13 when diagnosed, died at almost 16, a long life for a large dog.   


The medication removed the symptoms, so he didn't suffer.  


I'm praying she is OK.

Regular Contributor
Posts: 205
Registered: ‎12-10-2018

   I  adopted a dog with Cushings. She was diagnosed and on meds by the time I got her but it can take some time to get the meds adjusted correctly.  She was 12 when I got her and lived to 1 week before her 15 birthday. This was a few years ago and her meds were around $150 a month.  

   I don't want to scare you but my friend had a dog, last summer, that had the same symptoms and it turned out to be a rare form of diabetes. He only lived about 2 months. 

 I hope your pup is ok and it is nothing serious.

Respected Contributor
Posts: 2,763
Registered: ‎03-09-2010

@Puppy Lips   The test you are referencing is actually called an ACTH (adrenocorticotropic hormone) STIMULATION test, usually just called an ACTH stim test.  (Not related to the education programs highlighting science, technology, engineering and math, aka STEM.)


The ACTH stim test is used to test for both Cushing's Disease and Addison's Disease, but since you have a Siberian Husky, odds are the vet is more concerned with Cushing's, as Addison's tends to run in certain family groupings of dog breeds, and I don't believe Huskies are one of them, although, if your dog has been exposed to Agent Orange (the herbicide) it might have had adrenal gland damage that could cause Addison's.


The reason the vet has taken this step is that, most probably, the generalized bloodwork that has already been run showed normal kidney function, normal electrolytes, and liver damage, which is caused when Cushing's raises the cortisol level in your dog's body, which, over time, damages the liver.  The urinalysis probably showed no evidence of infection (blood, white blood cells, or bacteria) but was very dilute (aka watery).


The good news is that, if it is Cushing's, it is VERY easy to treat with one simple pill, given once or twice a day.  I have had several Cushing's dogs over the years, and the drug that we used to have to use, called Lysodren (chemically related to Agent Orange), is VERY toxic, and, if over-dosed, can destroy the adrenal glands, causing iatrogenic Addison's Disease.  (That happened to one of my dogs, when a vet school endocrinologist went against my expressed wishes and deliberately overdosed my dog, thankfully she did not die, but I had to use expensive injectible medicine for her for the rest of her life.)  The drug that is now FDA approved and the drug of choice is called trilostane, and is far, far safer to control the production of cortisol, because it works, not by chemically eroding the adrenal cells, but by interupting the chemical synthesis cycle of cortisol.  If an overdose starts to occur, you just withdraw the medicine until the dog recovers and begins showing symptoms of Cushing's again, then restart, perhaps at a lower dose.


I am sorry to hear you are dealing with a 15 year old with medical issues, my 16 year old Cairn Terrier, who we adopted 3 years ago, was born in a puppy mill (the people who surrendered him to the shelter admitted they bought him at a pet store) and has arthritis, hypothyroidism, and EPI, and is costing me well over $500 a month, and just a couple of weeks ago he jumped out of my mini-van instead of using the ramp and tore his cranial cruciate ligament (=human ACL) on his right hind leg,  and is getting laser therapy twice a week, since surgery isn't a good idea in such an old dog. 


Sometimes it really does seem that it never rains but it pours!  Hang tough, your Husky will soon be fine again.  My 12 year old Scottie was diagnosed with Cushing's a couple of years ago, takes his trilostane twice a day, and most people who meet him think he's a puppy, he acts so bouncy and playful.

Trusted Contributor
Posts: 1,760
Registered: ‎03-10-2010


[ Edited ]

Sorry, to hear about your doggies troubles!

You might want to try milk thistle. We had a dog that started drinking and peeing a lot and the vet prescribed 

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets


and it really improved his symptoms and liver blood counts a lot. It's a highly studied supplement (milk thistle) that should probably be given to all animals and people as well, really. It's useful for kidneys, liver, detox, diabetes, antioxidant support (I know it sounds like snake oil).

It's sold many places like Chewy. com, read the reviews and research milk thistle for dogs. Maybe it can help...

Hope you can find the answers!

"We can judge the heart of a man by his treatment of animals" -Immanuel Kant

"Once you have had a wonderful Dog, a life without one, is a life diminished"-Dean Koontz