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12-20-2019 07:54 AM - edited 12-20-2019 03:14 PM
There is a new warning about the use of Gabapentin respiratory complications in a drug safety communication issued today. If you use this medication you might want to read this and of course consult your physician or pharmacist if you have questions.
“FDA warns about serious breathing problems with seizure and nerve pain medicines gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR)
When used with CNS depressants or in patients with lung problems
12-19-2019
What safety concern is FDA announcing?
The U.S. Food and Drug Administration (FDA) is warning that serious breathing difficulties may occur in patients using gabapentin (Neurontin, Gralise, Horizant) or pregabalin (Lyrica, Lyrica CR) who have respiratory risk factors. These include the use of opioid pain medicines and other drugs that depress the central nervous system, and conditions such as chronic obstructive pulmonary disease (COPD) that reduce lung function. The elderly are also at higher risk.
Gabapentin and pregabalin are FDA-approved for a variety of conditions, including seizures, nerve pain, and restless legs syndrome.
Our evaluation shows that the use of these medicines, often referred to as gabapentinoids, has been growing for prescribed medical use, as well as misuse and abuse. ✅Gabapentinoids are often being combined with CNS depressants, which increases the risk of respiratory depression. ✅CNS depressants include opioids, anti-anxiety medicines, antidepressants, and antihistamines. ✅There is less evidence supporting the risk of serious breathing difficulties in healthy individuals taking gabapentinoids alone. We will continue to monitor these medicines as part of our routine monitoring of all FDA- approved drugs.”
Click on the words “drug safety communication” in paragraph 1, to read the link to the FDA communication.
12-20-2019 08:06 AM
Thank you for sharing this info. I was not aware of this , Used lyrica for years.
12-20-2019 08:56 AM - edited 12-20-2019 08:57 AM
So, it's Gabpentin in combination with other medicine that can cause breathing problems.
But Gabpentin by itself doesn't cause breathing problems.
12-20-2019 12:04 PM - edited 12-20-2019 12:19 PM
I take Gabapentin, it gave me back my life. I don't have any respiratory issues and I'm not taking any cns depressants so this does not apply to me. Honestly, when I weigh chronic disabling pain against the risks....I'd have to weigh them very carefully before I would consider going off the Gabapentin.
12-20-2019 12:05 PM
This is not really news to any of my doctors. They keep asking about how I am with the drug cocktail I am on.
12-20-2019 12:22 PM
Thank you for another interesting article Mindy. I appreciate any article that relates to public health or safety, because I love researching medical claims. Some turn out to be bogus, but are interesting nonetheless.
~~~All we need is LOVE💖
12-20-2019 12:23 PM
@Still Raining wrote:This is not really news to any of my doctors. They keep asking about how I am with the drug cocktail I am on.
It's not news to any doctor. Gabapentin has been around and in use for many years now, the risks and contraindications are know. However, they are prescribing it or off label uses now.
12-20-2019 03:06 PM
12-20-2019 03:11 PM
@chrystaltree wrote:I take Gabapentin, it gave me back my life. I don't have any respiratory issues and I'm not taking any cns depressants so this does not apply to me. Honestly, when I weigh chronic disabling pain against the risks....I'd have to weigh them very carefully before I would consider going off the Gabapentin.
@chrystaltree Hi Crystaltree. Just to be clear, here’s a quote from the warning.
Our evaluation shows that the use of these medicines, often referred to as gabapentinoids, has been growing for prescribed medical use, as well as misuse and abuse. Gabapentinoids are often being combined with CNS depressants, which increases the risk of respiratory depression. CNS depressants include opioids, anti-anxiety medicines, antidepressants, and antihistamines. There is less evidence supporting the risk of serious breathing difficulties in healthy individuals taking gabapentinoids alone. We will continue to monitor these medicines as part of our routine monitoring of all FDA- approved drugs.
12-20-2019 03:15 PM
@Still Raining wrote:This is not really news to any of my doctors. They keep asking about how I am with the drug cocktail I am on.
@Still Raining This is the first time that this warning is being sent to physicians and pharmacists.
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