Community Chat

[Mindy D]

---

@noodleann wrote:

---

@Mindy D wrote:

---

@deepwaterdotter wrote:

Hope this proves to be the vaccine that stops further proliferation of COVID.

---

The volunteers getting the weakest dose had antibodies at the same levels as persons that had recovered from the virus!

---

Has it been proven yet that having those antibodies confers protection? I thought that was a big unknown. One of many.

It must be exciting to be in medical R&D these days.

---

@noodleann This trial was primarily focused on safety. The results don't yet show whether people are prevented from infection.

[Mindy D]

---

@millieshops wrote:

@deepwaterdotterMe, too, but it's way too preliminary for me personally to decide the outer world is safe right now.   I don't have some magic number in my head, but 8 people out of 45 volunteers is only a sliver over 10% success,  

I know a sliver is enough to win a horse race -  hoping this sliver points to a health win as further experimentation goes on.

---

@millieshops @deepwaterdotter 

Moderna released antibody data for only eight participants, so far; four in th 25 mg group and four in the 100 mg group. It does not mean that these were the only results seen. I just means that these were the only released results. In the 25mg the four developed neutralizing antibodies at levels comparable to recovered COVID-19 patients. In the 100 mg group the antibodies "'significantly exceeded recovered patients." Moderna will be starting Phase 11. The purpose of the Phase 1 trial was to establish safety. 

[noodleann]

---

@Mindy D wrote:

---

@noodleann wrote:

---

@Mindy D wrote:

---

@deepwaterdotter wrote:

Hope this proves to be the vaccine that stops further proliferation of COVID.

---

The volunteers getting the weakest dose had antibodies at the same levels as persons that had recovered from the virus!

---

Has it been proven yet that having those antibodies confers protection? I thought that was a big unknown. One of many.

It must be exciting to be in medical R&D these days.

---

@noodleann What has been seen from the results of the trial is that the vaccine resulted in conferring the same level of immunity that  person that have recovered from COVOD-19 have had.

---

The same level of antibodies? Is it yet established that any level of antibodies confers immunity, thereby protecting from recurrence? I know it's assumed and hoped so, but is it yet documented?

I wonder if they're going to do a real challenge trial later on. I wonder whether they can prove it's protective without doing a challenge. I know they'd get volunteers, but yikes!

Thanks for reporting on this.

[Snowpuppy]

---

@RetRN wrote:

This news is certainly helping the markets today. Hope it continues and helps the economy come back. 

---

The news isnt helping markets. The Fed injecting cash is helping markets.

All sectors, commodities, oil, bonds all up? Fed buying spree after 3 down days.

[jeanlake]

Sounds like progress!

[suzyQ3]

We can only hope that this one or another one will prove to effective and safe. But I agree that of course we need to find out just what immunity means for those who have the antibodies or get them from a vaccine.

I'm going to assume that there will be no cutting corners to reach some magical date. A vaccine should go through all the phases until it as safe as any we have for other diseases.

[Snowpuppy]

And just as their stock jumped 20% on the news of clinical trials,  Moderma announced an after hours $1.25 B stock offering!

Of course all to cover the costs of research and I'm sure no board members will get a handsome payday.

[esmerelda]

In some people’s eyes pharma companies are bad no matter what. 

[Mindy D]

---

@noodleann wrote:

---

@Mindy D wrote:

---

@noodleann wrote:

---

@Mindy D wrote:

---

@deepwaterdotter wrote:

Hope this proves to be the vaccine that stops further proliferation of COVID.

---

The volunteers getting the weakest dose had antibodies at the same levels as persons that had recovered from the virus!

---

Has it been proven yet that having those antibodies confers protection? I thought that was a big unknown. One of many.

It must be exciting to be in medical R&D these days.

---

@noodleann What has been seen from the results of the trial is that the vaccine resulted in conferring the same level of immunity that  person that have recovered from COVOD-19 have had.

---

The same level of antibodies? Is it yet established that any level of antibodies confers immunity, thereby protecting from recurrence? I know it's assumed and hoped so, but is it yet documented?

I wonder if they're going to do a real challenge trial later on. I wonder whether they can prove it's protective without doing a challenge. I know they'd get volunteers, but yikes!

Thanks for reporting on this.

---

@noodleann @Just a brief overview of the types and mechanisms of acquired immunity and the research that supports some of these can be found here. https://www.ncbi.nlm.nih.gov/books/NBK8143/