So...I have been using Dr Denese for over a year. Hydroshield, Triple Strength Face & Neck Wrinkle Smoother, Peptide and Firming Pads Both and Neurotrophic as well. Well guess what?!? After watching Dimitri James and reading up on ingredients, all the reviews, as well as Paula's, I decided to give it a try. I got the Dermappeal, Collagenesis 24 Hr YPC & Ampules, Crease Release Day, along w his SPF 30 Anti-Aging Sunscreen and Intellitent CC. I'm 44 y/o normal skin w no acne or enlarged pores. I have terrible 11's, some pretty obvious vertical lip lines and am beginning to sag a bit along the jaw. I use my Clarisonic and whatever cleanser I happen to have recently purchased. Thoughts after ONE WEEK---I have seen more of an improvement in ALL my wrinkles and skin tone. This is after giving Denese a solid year to improve my skin. I love her and her products but never saw anything close to the results I am getting from SKINN. Really impressed although I felt a bit like I was buying my skincare at a flea market-just seems "cheap"-almost feel bad saying that but he is quite a character and w the exception of Heather Hall, I just can't tolerate the ShopHQ hosts and their constantly amazed gasps. My PMD is useless now using the Dermappeal. I have not tried Dr Denese's MD33 and am still considering it based on the reviews. Anybody else out there using SKINN or the MD33 that has comparison??? Apologies for typos-cannot type on tiny phone.