topic Re: PitDakota in Community Chat

PitDakota

Marp2 — Mon, 13 Oct 2014 00:54:57 GMT

Please let me know when you are here. Thanks.

Re: PitDakota

dmod nj — Mon, 13 Oct 2014 01:13:12 GMT

Hi Marp,

Please feel free to post your shout out to pitty on my thread. If she logs on, she is sure to see it there.

Re: PitDakota

Marp2 — Mon, 13 Oct 2014 01:16:07 GMT

Thanks dmod. I'll do that.

Re: PitDakota

dmod nj — Mon, 13 Oct 2014 01:16:46 GMT

Anytime Marp. You are always welcome.

Re: PitDakota

dooBdoo — Mon, 13 Oct 2014 01:20:56 GMT

Hi, Marp and dmod! I wish she would appear and add her comments to the latest RRR thread. I wish I had copied what she wrote not long ago, about her views on that particular situation. It was so insightful and helpful, in my opinion. Just like everything she contributes here.

Re: PitDakota

pitdakota — Mon, 13 Oct 2014 03:07:49 GMT

Marp, I am here.

Re: PitDakota

pitdakota — Mon, 13 Oct 2014 03:09:03 GMT

On 10/12/2014 dooBdoo said:
Hi, Marp and dmod! I wish she would appear and add her comments to the latest RRR thread. I wish I had copied what she wrote not long ago, about her views on that particular situation. It was so insightful and helpful, in my opinion. Just like everything she contributes here.

Aww, how thoughtful of you dooBdoo. Glad something that I said was insightful and helpful. Mark that down. LOL! Good to see you.

Re: PitDakota

cody2 — Mon, 13 Oct 2014 03:12:14 GMT

I am with the rest of you here. Pitty is a treasure on this board!

Re: PitDakota

dooBdoo — Mon, 13 Oct 2014 03:12:45 GMT

On 10/12/2014 pitdakota said:
On 10/12/2014 dooBdoo said:
Hi, Marp and dmod! I wish she would appear and add her comments to the latest RRR thread. I wish I had copied what she wrote not long ago, about her views on that particular situation. It was so insightful and helpful, in my opinion. Just like everything she contributes here.

Aww, how thoughtful of you dooBdoo. Glad something that I said was insightful and helpful. Mark that down. LOL! Good to see you.

You're a gem, pitdakota. Thanks, always good to see you.

Re: PitDakota

Sushismom — Mon, 13 Oct 2014 03:14:01 GMT

Pit usually gives great advice and info. She knows what she's talking about and keeps a calm head.

Re: PitDakota

JustJazzmom — Mon, 13 Oct 2014 03:15:20 GMT

Waving to Pit!!

Re: PitDakota

kdgn — Mon, 13 Oct 2014 03:18:01 GMT

Pity- Marp left you a link on Donna's thread regarding the announcement on Alzheimer's.

Re: PitDakota

pitdakota — Mon, 13 Oct 2014 03:25:41 GMT

Geez everyone. Good to see everyone though!!

Thanks kdgn....I just posted in the house and missed the link. I saw Marp's post. Geez, I must still be sleep deprived and worn out from yesterday.

I will go take a look. Thanks kdgn!

Re: PitDakota

Lila Belle — Mon, 13 Oct 2014 03:26:50 GMT

pidakota's the best !

I really admire you and the work you do.

Re: PitDakota

pitdakota — Mon, 13 Oct 2014 03:27:03 GMT

kdgn, that link takes me to this thread.

Re: PitDakota

Marp2 — Mon, 13 Oct 2014 03:29:52 GMT

Hi Pit, so glad you stopped by tonight. Earlier I read an exciting article that I would like you to take a look at (it is brief) and give your opinion on the findings and a brief outline of the procedures that will be followed to bring this to fruition if it stands up to peer review and independent scrutiny.

For the first time, and to the astonishment of many of their colleagues, researchers created what they call Alzheimer’s in a Dish — a petri dish with human brain cells that develop the telltale structures of Alzheimer’s disease. In doing so, they resolved a longstanding problem of how to study Alzheimer’s and search for drugs to treat it; the best they had until now were mice that developed an imperfect form of the disease.

The key to their success, said the lead researcher, Rudolph E. Tanzi of Massachusetts General Hospital in Boston, was a suggestion by his colleague Doo Yeon Kim to grow human brain cells in a gel, where they formed networks as in an actual brain. They gave the neurons genes for Alzheimer’s disease. Within weeks they saw the hard Brillo-like clumps known as plaques and then the twisted spaghetti-like coils known as tangles — the defining features of Alzheimer’s disease.

Balance of article: http://www.msn.com/en-us/news/us/researchers-replicate-alzheimer%E2%80%99s-brain-cells-in-a-petri-dish/ar-BB8W5er

Re: PitDakota

pitdakota — Mon, 13 Oct 2014 03:30:39 GMT

Hey, hey....the gang is all here.

Well except for Marp.

We have an amazing group of women on these boards!!

JustJazzMom....I saw the Linea thread you were talking about a little while ago. I am in sooooo much trouble. But a girl has to have very nice clothes for work. That is my story and I am sticking to it!!!

Re: PitDakota

pitdakota — Mon, 13 Oct 2014 03:31:30 GMT

Okay Marp, let me go take a look.

Re: PitDakota

pitdakota — Mon, 13 Oct 2014 03:47:03 GMT

On 10/12/2014 Marp2 said:
Hi Pit, so glad you stopped by tonight. Earlier I read an exciting article that I would like you to take a look at (it is brief) and give your opinion on the findings and a brief outline of the procedures that will be followed to bring this to fruition if it stands up to peer review and independent scrutiny.

For the first time, and to the astonishment of many of their colleagues, researchers created what they call Alzheimer’s in a Dish — a petri dish with human brain cells that develop the telltale structures of Alzheimer’s disease. In doing so, they resolved a longstanding problem of how to study Alzheimer’s and search for drugs to treat it; the best they had until now were mice that developed an imperfect form of the disease.

The key to their success, said the lead researcher, Rudolph E. Tanzi of Massachusetts General Hospital in Boston, was a suggestion by his colleague Doo Yeon Kim to grow human brain cells in a gel, where they formed networks as in an actual brain. They gave the neurons genes for Alzheimer’s disease. Within weeks they saw the hard Brillo-like clumps known as plaques and then the twisted spaghetti-like coils known as tangles — the defining features of Alzheimer’s disease.

Balance of article: http://www.msn.com/en-us/news/us/researchers-replicate-alzheimer%E2%80%99s-brain-cells-in-a-petri-dish/ar-BB8W5er

Wow, how exciting!! I had heard that they had previously tried to generate plaques and tangles in liquids and ultimately were not able to do so successfully. But I had not heard this news.

The latest I had heard was a few months ago about the success of using retinal scans to detect the beta-amyloid plaques associated with Alzheimer's disease. And since beta-amyloid plaques are only associated with Alzheimer's it seems a sure fire way to diagnose or catch it early.

However, that is after the fact. If they can subject these beta-amyloid plaques and tangles to various medications and study the effect that will be phenomenal. Then fingers crossed they can find a medication currently in use for something that is safe that would preclude the development of plaques. That would be the best case scenario!!

Re: PitDakota

Marp2 — Mon, 13 Oct 2014 03:53:02 GMT

Thanks Pit. I got so excited when I read that article that I wanted to be sure I wasn't overlooking something that was an obvious overstatement. Of course my brain also went of a flight of fancy and I started asking:

Since it appears that plaque and tangles have a symbiotic relationship I'm particularly interested in whether interrupting the symbiosis will halt progression.

Another thought I've had has to do with plaque itself. Mom had scans a number of years before she became symptomatic with dementia that revealed numerous plaque spots (unknown type). My nephew has MS with an unusual amount of brain plaque. If the plaque could be dissolved or halted could that prevent, halt or reverse dementia and/or the effects of MS?

So many possibilities if this research and the technique proves itself, not only for brains but the entire body.