topic Re: convalescent plasma? in Wellness

convalescent plasma?

granddi — Mon, 30 Nov 2020 23:36:22 GMT

Has anyone been treated with convalescent plasma?

Did your doctor have to apply for its use?

Please share you experience, Thanks

Re: convalescent plasma?

de1rdre — Tue, 01 Dec 2020 00:23:59 GMT

Most recent FDA rules on use of convalescent plasma:

https://www.fda.gov/vaccines-blood-biologics/investigational-new-drug-ind-or-device-exemption-ide-process-cber/recommendations-investigational-covid-19-convalescent-plasma#Collection

Re: convalescent plasma?

granddi — Tue, 01 Dec 2020 01:08:56 GMT

The FDA has approved its use on an emergency basis.

A TV doc said that they have to apply to the FDA to use it and this often is a long process.

It is not for use for hospitalized COVID patients or patients using oxygen. It is apparently intended for mild to moderate cases.

If so, I wonder if it is being offered to newly diagnosed cases?

Were you offered this therapy when you were diagnosed?

The Mayor of Fort Worth just discussed getting this 90 minute infusion and felt wonderful after just a few hours. The president said something similar about his experience.

I was just wondering if this therapy is widely available or limited.

Re: convalescent plasma?

Drythe — Sun, 06 Dec 2020 02:49:35 GMT

I believe they gave Monoclonal Antibodies at Walter Reed.

Edited for brain wave.

Re: convalescent plasma?

red&curly — Tue, 01 Dec 2020 02:09:06 GMT

It was on Myrtle Beach news that one hospital Tidewater was given only a handful.

Doctor said they would be given to people that don't need to be hospitalized in order to keep those beds open.

Re: convalescent plasma?

Growing — Tue, 01 Dec 2020 17:16:24 GMT

My cardiologist was teling me how awful it was that people were not getting the medical care (treatments/medications) that would really help them in relation to the virus. A mayor in a city near to us got the convelescent plasma and said she was almost immediately well. How she got it when the supply is so low is having pull and being the mayor! My understanding is that this treatment is mostly used in hospitals for the really sick.

Re: convalescent plasma?

SilleeMee — Tue, 01 Dec 2020 17:40:23 GMT

How much does the conval plasma for covid cost? Insurance does not cover the cost of it because it hasn't been cleared for regular use.

Re: convalescent plasma?

Mindy D — Tue, 01 Dec 2020 23:36:32 GMT

@granddi wrote:
The FDA has approved its use on an emergency basis.
A TV doc said that they have to apply to the FDA to use it and this often is a long process.

It is not for use for hospitalized COVID patients or patients using oxygen. It is apparently intended for mild to moderate cases.
If so, I wonder if it is being offered to newly diagnosed cases?
Were you offered this therapy when you were diagnosed?

The Mayor of Fort Worth just discussed getting this 90 minute infusion and felt wonderful after just a few hours. The president said something similar about his experience.

I was just wondering if this therapy is widely available or limited.

@granddi The President did not have convalescent plasma.

Re: convalescent plasma?

Mindy D — Tue, 01 Dec 2020 23:59:08 GMT

@Drythe wrote:
I believe they gave Monoclonal Plasma at Walter Reed.

@Drythe Reed used Regeneron, not convalescent plasma. Regeneron uses monoclonal antibodies. He also had an antiviral med, Remdesivir, and a steroid plus zinc, vitamin D, famotidine (the medication in Pepcid, for heartburn or acid reflux), melatonin and a daily aspirin

Re: convalescent plasma?

Mindy D — Wed, 02 Dec 2020 00:20:41 GMT

The step daughter of our best friend put out a plea for convalescent plasma donors for her bio dad. He had COVID. He did get the plasma but he unfortunately died.

Re: convalescent plasma?

granddi — Wed, 02 Dec 2020 00:58:18 GMT

@Mindy D wrote:
@Drythe wrote:
I believe they gave Monoclonal Plasma at Walter Reed.
@Drythe Reed used Regeneron, not convalescent plasma. Regeneron uses monoclonal antibodies. He also had an antiviral med, Remdesivir, and a steroid plus zinc, vitamin D, famotidine (the medication in Pepcid, for heartburn or acid reflux), melatonin and a daily aspirin

I think another monlclonal is by Lilly called bamlanivimab.

I heard a discussion that we have the treatment to keep people out of hospitals. The idea is to aggressively treat positive cases that fall within high risk metrics.

Someone here can clarify my understanding. The monoclonal plasma is lab created antibodies vs the convalescent plasma derives the antibodies from those who have recovered from the virus.

It sounds like most positive cases are given palative care instructions with the caution to return if conditions worsen. I was wondering why more people are not more aggressively treated when first diagnosed. I assume the reason is a shortage of both convalescent and monoclonal antibody therapy. Some vip's report getting the therapy but I wondered if anyone knew of a regular someone able to get the infusion.

I'm not even asking if insurance covers the therapy. I'm wondering how available is one of the covid antibody therapies?

Re: convalescent plasma?

SilleeMee — Wed, 02 Dec 2020 01:34:33 GMT

Monoclonal antibodies are some of the most expensive and difficult to make drugs in the world. That might be why they are not more readily available.

Monoclonal antibodies are not mass produced but produced only in small quantities.