topic Re: Famotidine in Wellness

Famotidine

goldensrbest — Sun, 04 Oct 2020 11:22:03 GMT

Lots of talk about this acid reducer on fb, about covid 19,how could it help with this virus?

Re: Famotidine

SilleeMee — Sun, 04 Oct 2020 16:44:59 GMT

It's being repurposed to use as an antiviral drug and is not being used as an acid reducer for covid patients. Famotidine has been shown to interfere with the virus reproduction cycle by blocking a cellular enzyme needed to complete that cycle, resulting in lower viral loads.

Techical read here:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324004/

Re: Famotidine

goldensrbest — Sun, 04 Oct 2020 12:00:59 GMT

Quite interesting i find it. Would not had thought of using it for this virus.

Re: Famotidine

Kachina624 — Sun, 04 Oct 2020 16:40:39 GMT

It's ordinary Pepcid which is an acid reducer I take every day for acid reflux. I wish people would quit spreading rumors about it preventing/curing CoVi19. This went around last spring and I was unable to find it anywhere for several months. I need it badly. I seriously doubt it has any effect on the virus.

Re: Famotidine

goldensrbest — Sun, 04 Oct 2020 18:14:49 GMT

@Kachina624 wrote:
It's ordinary Pepcid which is an acid reducer I take every day for acid reflux. I wish people would quit spreading rumors about it preventing/curing CoVi19. This went around last spring and I was unable to find it anywhere for several months. I need it badly. I seriously doubt it has any effect on the virus.

That is what i am trying to find out, if it is true,or not.

Re: Famotidine

Porcelain — Sun, 04 Oct 2020 19:13:13 GMT

The paper @SilleeMee provided did not say conclusively whether it does anything one way or another. It said it was an avenue for scientists to explore, based on one set of anecdotal observations. It also said there may be risks to taking antacids because it is possible they increase the Covid GI infection aspect of the disease by inhibiting stomach acid.

If you want to take this, I'd say ask your doctor about it and go with their guidance.

Re: Famotidine

SilleeMee — Sun, 04 Oct 2020 19:17:16 GMT

Exactly. @Porcelain Nothing so far is confirmed nor has it's use as an antiviral been established as being safe and w/o side effects. It's just too soon to say.

Re: Famotidine

goldensrbest — Sun, 04 Oct 2020 19:17:52 GMT

Like i said fb was just alive with this last night,i thought WHAT?, so i asked on here, from what i have found the study was very small, so there you go.

Re: Famotidine

brandiwine — Sun, 04 Oct 2020 19:21:55 GMT

@Kachina624 You are 100% correct. No proof it's an anti viral. Too much bad info out there.

Re: Famotidine

Toppers3 — Sun, 04 Oct 2020 19:43:13 GMT

@Kachina624 wrote:
It's ordinary Pepcid which is an acid reducer I take every day for acid reflux. I wish people would quit spreading rumors about it preventing/curing CoVi19. This went around last spring and I was unable to find it anywhere for several months. I need it badly. I seriously doubt it has any effect on the virus.

I remember this too, and some of us were posting about it here on the forum.

I also had trouble finding it, both physically in the stores and online.

I couldn't seem to find it anywhere.

I was buying the over-the-counter plain, generic Famotodine.

I ended up having to get a prescription from our doctor for it, rather than trying to find the OTC version.

When my prescription comes up next month for renewel, I'll have to see if it's available again or not.

Re: Famotidine

granddi — Sun, 04 Oct 2020 20:04:42 GMT

NIH is a rock sold source for information on drug studies.

To me the post was just sharing an interesting study and not suggesting that everyone should be taking Pepsid.

There must be something there there bc it is included in the preventative care for some individuals. It's part of the COVID cocktail.

Re: Famotidine

Lali1 — Sun, 04 Oct 2020 20:12:01 GMT

@granddi wrote:
NIH is a rock sold source for information on drug studies.
To me the post was just sharing an interesting study and not suggesting that everyone should be taking Pepsid.

There must be something there there bc it is included in the preventative care for some individuals. It's part of the COVID cocktail.

You're correct. If adults are dumb enough to take every little pill everyone on the internet suggests then maybe they need to be cared for and not allowed to care for themselves without supervision.

Re: Famotidine

Kachina624 — Sun, 04 Oct 2020 20:36:52 GMT

@Toppers3 It's available right now on Amazon. I just ordered a good supply. Just recently reappeared after the run on it. Yesterday I noticed it listed as an ingredient in the experimental "cocktail" they're giving CoVi19 patients, or one in particular. That probably means the run will be on again.

Re: Famotidine

EatWell — Sun, 04 Oct 2020 21:17:28 GMT

Ever since a notable government offiicial contracted Covid-19, he was supposedly getting this for the virus, there has been a run on Famotidine (Pepsid). My local drugstore is totally out of it.

~Please do your part. Wear a mask, observe social distancing, wash hands. It is patriotic, and the right thing to do.~😷🇺🇸

Re: Famotidine

Icegoddess — Sun, 04 Oct 2020 21:31:50 GMT

Well, there is this study: https://hartfordhealthcare.org/about-us/news-press/news-detail?articleId=28305&publicid=497

I take a ppi, but I keep Pecid Complete for times when I have breakthrough issues. It was the only thing that seemed to work. It was off the shelves for a couple of years awhile back (way before Covid) for some reason. I was so glad to see it back on the shelves.

Re: Famotidine

Mindy D — Sun, 04 Oct 2020 22:45:58 GMT

the results of the recent cohort study in New York were promising. The study showed that famotidine use was associated with reduced risk for intubation or death among hospitalized COVID-19 patients (adjusted hazard ratio 0.42, 95% CI 0.21–0.85) [4].https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324004/

"This retrospective study found that, in patients hospitalized with COVID-19, famotidine use was associated with a reduced risk of clinical deterioration leading to intubation or death. The study was premised on the assumption that use of famotidine represented a continuation of home use, but documentation of why famotidine was given was poor. The results were specific for famotidine (no protective association was seen for PPIs) and also specific for COVID-19 (no protective association in patients without COVID-19). A lower peak ferritin value was observed among users of famotidine, supporting the hypothesis that use of famotidine may decrease cytokine release in the setting of SARS-CoV-2 infection. A randomized controlled trial is currently under way to determine whether famotidine can improve clinical outcomes in hospitalized patients with COVID-19 (NCT04370262)."

4.Freedberg DE, Conigliaro J, Sobieszczyk ME, et al. Famotidine use is associated with improved clinical outcomes in hospitalized COVID-19 patients: A Propensity score matched retrospective cohort study. Gastroenterology. 2020 doi: 10.1053/j.gastro.2020.05.053. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

Re: Famotidine

Toppers3 — Sun, 04 Oct 2020 23:45:19 GMT

Thanks for the information, and for your help @Kachina624.

It's greatly appreciated!

Re: Famotidine

vsm — Mon, 05 Oct 2020 01:22:35 GMT

@Kachina624 wrote:
It's ordinary Pepcid which is an acid reducer I take every day for acid reflux. I wish people would quit spreading rumors about it preventing/curing CoVi19. This went around last spring and I was unable to find it anywhere for several months. I need it badly. I seriously doubt it has any effect on the virus.

So doctors who have concluded that this widely available generic drug is likely to help their Covid patients should forgo prescribing it because you "seriously doubt it has any effect on the virus"?

Re: Famotidine

AngelPuppy1 — Mon, 05 Oct 2020 10:57:00 GMT

I've taken this for years as prescribed by my doctor. They were touting this months ago for the virus and then I couldn't even get my prescription! Every time they put this on the news, everybody goes nuts and buys it up and then I can't get the medicine I should have! Ridiculous.....

Re: Famotidine

FLgardener — Mon, 05 Oct 2020 15:22:17 GMT

I have taken famotidine for years and always need to have it on hand. I did order 200 from Amazon this morning.

Is my need any more important than anyone else's need? I don't think I should determine that. I won't fault anyone for stocking up in these uncertain times.