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Stomach problems with metformin?

Started 1287086395.743 in Viewpoints | Last reply 1287153004.133 by thalmy

I am having alot of stomach distress with metformin. I read that the extended release is better so my dr. switched me to that. She has me taking 2 500mg with breakfast and another 2 500mg at dinner. I take these with food. I have the feeling in my stomach similar to the way it feels if I take un buffered aspirin. It tears it up inside. That is the only way to explain the feeling. I only take buffered pain relievers and usually can't take any on an empty stomach. I am going to ask my dr.., but was wondering if there are other meds for diabetes that don't hurt the stomach, or if there is something I can do to relive the pain. I take pepto bismal and sometimes that seems to help, but I am leery of taking it every day. Also, eating seems to help for a little while but then it comes back. Any suggestions will be appreciated. thanks

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chprsp1287086627.214246 PostsRegistered 9/5/2007

Definitely talk to your doctor about the problem. DH has been on 850 mg of metformin twice a day along with insulin shots for years.. 2500 mg seems like a large dose.

leehare1287086854.781805 PostsRegistered 4/7/2010

not knowing any actual medical stuff-I only can recount my experience-after taking metformin for a few years-I lost a considerable amount of weight and now do not need to take any more.--I have read that as little as 20-30 pounds can have a dramatic effect on the need for meds. And that is not to say that there are not diabetics who are not overweight-losing the weight was not a piece of cake (ha)-but the benifits were great. now that is just me-not everyone.

Wiskota1287087085.397797 PostsRegistered 1/24/2008Wisconsin
On 10/14/2010 chprsp said:

Definitely talk to your doctor about the problem. DH has been on 850 mg of metformin twice a day along with insulin shots for years.. 2500 mg seems like a large dose.

I thought the same thing you did 2500 mgs - but after rereading it she meant she takes TWO 500 mg for a total of 1000. I take it also, but don't have any problems with my stomach. This really is a question for your doctor and she can suggest another med. There are many.

"I'm proud to be an American, where at least I know I'm free. And I want to thank the men who died who give that right to me." Lee Greenwood

RickyRocky1287087475.837736 PostsRegistered 2/16/2007

The thing that helped me with this issue was drinking lots and lots of water.

57babe1287087750.9278638 PostsRegistered 8/21/2010

Yes, metformin causes stomach problems. I'm not sure what can be done about it. Some diabetics can't handle the side effects. Good idea to ask the doctor and research it yourself on drugs.com. Hope you are feeling better soon.


MaggieToo1287088314.5378475 PostsRegistered 10/6/2004AZ

I couldn't handle Metformin or Glyburide. One or both nearly ruined my kidneys. After about two weeks on first one then the other, I could hardly move, could hardly walk across the room, had to physically hold my head up with my hand.

I stopped them altogether and try to control the diabetes with just diet. I don't know if there is another drug I can take or not.

There are none so blind as those who will not see.

msme1287088350.043280 PostsRegistered 12/24/2005
On 10/14/2010 chprsp said:

Definitely talk to your doctor about the problem. DH has been on 850 mg of metformin twice a day along with insulin shots for years.. 2500 mg seems like a large dose.

Sorry, its only 2000 a day. Since extended release only come in 500mg...I take two 500mg twice a day.

msme1287104060.493280 PostsRegistered 12/24/2005
On 10/14/2010 RickyRocky said:

The thing that helped me with this issue was drinking lots and lots of water.

Can you give me more on this? did you drink alot all day? right after taking it? were you able to continue with just water drinking? the drug info does say something like drink plenty of fluids. thanks

India Rose1287108251.8334209 PostsRegistered 4/30/2007

msme - I have had bad experiences with Metformin and its sibling Actos. Do you want expert care for diabetes? See an endocrinologist. Family physicians do not have the expertise to treat diabetes which is why we have specialists.

"Freedom is lost gradually from an uninterested, uninformed, and uninvolved people".
Thomas Jefferson

adelle381287109313.2079474 PostsRegistered 12/22/2007

Definitely see your doctor ASAP.

"Fear always springs from ignorance."
Ralph Waldo Emerson

drizzellla1287109717.191555 PostsRegistered 7/16/2007

Thanks for writing this post. I recently started taking Metformin. I take 500mg a day but I take it on an empty stomach. I had not noticed stomach troubles but it seems my lunch does not stay with me for long after I eat it. And lunch is about 3 hours after I take Metformin. I was wondering if that was the reason. Thanks for the post, maybe I should read more about it.

The bad news is Time Flies
The good news is You are the pilot.

Js41287110286.497251 PostsRegistered 9/15/2010

My S-I-L was on it and felt as she had the flu but eventually was okay. The dose was increased and the feeling of the flu came back but is okay now too.

One of my DDs is on it and it bothers her. It is a periodic thing with her. Some days she has stomachaches or is hitting Imodium and other times is fine.

Hope you get adjusted to it and feel better soon.

Jeanne

Last edited on 10/14/2010

Last edited on 10/14/2010

GrannySher­ry1287116086.26720 PostsRegistered 1/26/2010Proud So. Cal. South Bay native now in WA state

SEE YOUR DOCTOR ASAP.

ivey1287116506.633209 PostsRegistered 6/25/2007

I take Metformin, and it does kind of give me a queasy stomach that will go away. However, the part I hate is the diarrhea out of nowhere. That side effect is a bad one.

Have you ever tried Byetta or Victoza with it? Wow, those two made me very nauseated. You have to just tell your doctor and play a little detective work. Good luck to you.

Foxglove1287117649.8934931 PostsRegistered 7/2/2007
On 10/14/2010 drizzellla said:

Thanks for writing this post. I recently started taking Metformin. I take 500mg a day but I take it on an empty stomach. I had not noticed stomach troubles but it seems my lunch does not stay with me for long after I eat it. And lunch is about 3 hours after I take Metformin. I was wondering if that was the reason. Thanks for the post, maybe I should read more about it.

You are really suppose to take it with food. I have been taking it for years and my doctor warned me of the side effects as upset stomach and diareha, but those things have seemed to disappear over the years for me. I would try taking it before meals and see if it makes a difference.

It is easier to fool people than convince them that they have been fooled~~Mark Twain

Yep, here I am, right on time!

drizzellla1287140199.4731555 PostsRegistered 7/16/2007

Thanks Foxglove - I will take it with food from now on. I think I read the drug instructions when I first took it but then I kept forgetting to take the Matformin and started taking if when I remembered.

The bad news is Time Flies
The good news is You are the pilot.

AngelPuppy11287140257.018800 PostsRegistered 5/26/2008

DH spent a lot of time in the bathroom when he first began taking this. It is better now but he still has more trouble with his stomach than he ever did. Before taking this med, he had a cast-iron stomach. Not any more.

"A day without sunshine is like, you know, night." - Steve Martin.

RickyRocky1287145968.957736 PostsRegistered 2/16/2007
On 10/14/2010 msme said:
On 10/14/2010 RickyRocky said:

The thing that helped me with this issue was drinking lots and lots of water.

Can you give me more on this? did you drink alot all day? right after taking it? were you able to continue with just water drinking? the drug info does say something like drink plenty of fluids. thanks

msme: I drink lots of water when I take it and I continue to drink water all day. I would try to drink at least a 12 oz glass when you take your pill. Maybe wait a half hour and then drink another 12 oz glass. Sometimes if I feel my stomach starting to feel yucky after I take the pill, I will get another big glass of water and the yucky feeling will go away.

I sure hope this helps you. It's not any fun to feel sick after taking your meedication.

SweetWood ­Max1287146335.8612239 PostsRegistered 9/7/2010

Our office orders this for pts everyday so I hear this daily. Yes the Xr is much easier but Metformin in general will cause all this. Husband just started taking it as well and it tore his stomach up for about 3 weeks. I would think after that you should be getting use to it. If not call your doctor. Of all those types of medications they say Metformin (glucophage) is the best, so give it some time. Also, it's quite inexpensive. Just make sure you eat when you take it and probably eat something smaller throughout the day, ie crackers, etc.

Give it a little time and remember that medication is brutal to begin taking!

Also known as Maxs-Grandma!


Laundry is the only thing that should be separated by color

FrostyBabe1287146942.683195 PostsRegistered 10/6/2004in the vicinity of an area adjacent to a location

I started taking Metformin 3-4 years ago for PCOS and did have aome stomach upset while I was getting used to the medication. My doctor gradually increased the dosage over a couple of weeks, but I still had some discomfort. It was made very clear to me that it needs to be taken with meals. Even now, it helps me "police" my food choices - if I eat something greasy/fried it's a bad thing pretty quickly.

Happiness is an attitude. We either make ourselves miserable, or happy and strong. The amount of work is the same. ~ Francesca Reigler

msme1287148771.59280 PostsRegistered 12/24/2005
On 10/14/2010 GrannySherry said:

SEE YOUR DOCTOR ASAP.

I am seeing my dr. regularly and have been on this for awhile. Just recently it started bothering me alot. I have IBS, so I don't attribute those types of symptoms to the Metformin. What I have bothering me most recently is just a stomach that hurts...the same feeling I get if taking an asprin or excedrin on an empty stomach. It is a grinding, sort of like indegestion in the stomach. Very uncomfortable. I am taking it with food but for about 3 hours after taking it, my stomach bothers me. I am taking it at breakfast and dinner, so by the time I have to take it again, my stomach has settled down, but starts again when taken at dinner. it is very frustrating. I am wondering if it is something that I am eating as another poster mentioned? I will drink lots of water and see if this helps. and of course contact my dr if I feel too bad, but otherwise I have to take it so I guess I just have to keep popping the pepto...

banjo1287149032.675243 PostsRegistered 6/16/2006Nebraska

I take Metformin and have had no problems with it. I take it right after meals and have no stomach problems. However, I would talk to my Dr. if I were having any difficulties.

You can tell who the strong women are, they are the ones building each other up, instead of tearing each other down!

ivey1287149335.43209 PostsRegistered 6/25/2007

Have any of you ever noticed the strong fishy smell that the bottle of pills have? I was concerned about it, and there are a lot of posts on the internet about the smell. I get mine through mail order CVS, and called a pharmacist there. He had to ask around to the others for an answer. They finally decided it's the like the sulfur component to it. Anyway, I empty the bottle of the pills and let them sit in a dish for about a day and they "air" out and are ok.

circles1287149654.117694 PostsRegistered 5/11/2005N.J.

I take metformin...500mg...once a day with food....2500mg twice a day seems excessive...I don't have any stomach problems with it...check with your doctor...

LipstickDi­va1287152490.04739197 PostsRegistered 4/22/2005On the Lake in Ohio

One of the side effects of Metformin is this stomach distress. My DH has been taking it for about 2 months and for the first 2 weeks had ummm, "distress." He thought he was going to have to quit taking it. The problems worked themselves out after the 2 weeks which is the normal timeframe. He is not on ER and takes 850mg twice a day.

We just finished up a diabetes education class and the nurse said if you are having stomach problems to take the pills right after you eat instead of before and stometimes that will help.

You can't buy love but you can adopt it. Adopt, don't shop.

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